Endothelial cell metabolism
G Eelen, P de Zeeuw, L Treps, U Harjes… - Physiological …, 2018 - journals.physiology.org
Endothelial cells (ECs) are more than inert blood vessel lining material. Instead, they are
active players in the formation of new blood vessels (angiogenesis) both in health and (life …
active players in the formation of new blood vessels (angiogenesis) both in health and (life …
Vascular heterogeneity and specialization in development and disease
M Potente, T Mäkinen - Nature Reviews Molecular Cell Biology, 2017 - nature.com
Blood and lymphatic vessels pervade almost all body tissues and have numerous essential
roles in physiology and disease. The inner lining of these networks is formed by a single …
roles in physiology and disease. The inner lining of these networks is formed by a single …
The role of the VEGF family in coronary heart disease
Y Zhou, X Zhu, H Cui, J Shi, G Yuan, S Shi… - Frontiers in …, 2021 - frontiersin.org
The vascular endothelial growth factor (VEGF) family, the regulator of blood and lymphatic
vessels, is mostly investigated in the tumor and ophthalmic field. However, the functions it …
vessels, is mostly investigated in the tumor and ophthalmic field. However, the functions it …
Vascular endothelial growth factor signaling in development and disease
S Karaman, VM Leppänen, K Alitalo - Development, 2018 - journals.biologists.com
Vascular endothelial growth factors (VEGFs) are best known for their involvement in
orchestrating the development and maintenance of the blood and lymphatic vascular …
orchestrating the development and maintenance of the blood and lymphatic vascular …
Endothelial cell metabolism in normal and diseased vasculature
G Eelen, P De Zeeuw, M Simons… - Circulation research, 2015 - Am Heart Assoc
Higher organisms rely on a closed cardiovascular circulatory system with blood vessels
supplying vital nutrients and oxygen to distant tissues. Not surprisingly, vascular pathologies …
supplying vital nutrients and oxygen to distant tissues. Not surprisingly, vascular pathologies …
Lacteal junction zippering protects against diet-induced obesity
Excess dietary lipid uptake causes obesity, a major global health problem. Enterocyte-
absorbed lipids are packaged into chylomicrons, which enter the bloodstream through …
absorbed lipids are packaged into chylomicrons, which enter the bloodstream through …
[HTML][HTML] VEGFR1 signaling in retinal angiogenesis and microinflammation
Five vascular endothelial growth factor receptor (VEGFR) ligands (VEGF-A,-B,–C,-D, and
placental growth factor [PlGF]) constitute the VEGF family. VEGF-A binds VEGF receptors 1 …
placental growth factor [PlGF]) constitute the VEGF family. VEGF-A binds VEGF receptors 1 …
Cardiomyocyte—endothelial cell interactions in cardiac remodeling and regeneration
The heart is a complex organ consisting of various cell types, each of which plays an
important role in both physiological and pathophysiological conditions. The cells …
important role in both physiological and pathophysiological conditions. The cells …
Endothelial cell–cardiomyocyte crosstalk in heart development and disease
The crosstalk between endothelial cells and cardiomyocytes has emerged as a requisite for
normal cardiac development, but also a key pathogenic player during the onset and …
normal cardiac development, but also a key pathogenic player during the onset and …
VEGFB/VEGFR1-induced expansion of adipose vasculature counteracts obesity and related metabolic complications
Impaired angiogenesis has been implicated in adipose tissue dysfunction and the
development of obesity and associated metabolic disorders. Here, we report the unexpected …
development of obesity and associated metabolic disorders. Here, we report the unexpected …