Decoding the role of miRNAs in multiple myeloma pathogenesis: A focus on signaling pathways

AM Yehia, EGE Elsakka, AI Abulsoud… - … -Research and Practice, 2023 - Elsevier
Multiple myeloma (MM) is a cancer of plasma cells that has been extensively studied in
recent years, with researchers increasingly focusing on the role of microRNAs (miRNAs) in …

The emerging role of miRNAs in Merkel cell carcinoma pathogenesis: Signaling pathway crosstalk

NI Rizk, HM Midan, GK Helal, AI Abulsoud… - … -Research and Practice, 2023 - Elsevier
Merkel cell carcinoma (MCC) is an uncommon invasive form of skin cancer that typically
manifests as a nodule on the face, head, or neck that is flesh-colored or bluish-red in …

miRNAs driving diagnosis, prognosis and progression in Merkel cell carcinoma

TM Al-Noshokaty, MS Elballal, GK Helal… - … -Research and Practice, 2023 - Elsevier
Merkel cell carcinoma (MCC) is a rare, aggressive form of skin malignancy with a high
recurrence commonly within two to three years of initial diagnosis. The incidence of MCC …

The protective potential of alpha lipoic acid on amiodarone-induced pulmonary fibrosis and hepatic injury in rats

G Ibrahim Fouad, M R. Mousa - Molecular and Cellular Biochemistry, 2021 - Springer
Amiodarone (AMD) is a widely used antiarrhythmic drug prescribed to treat cardiac
tachyarrhythmias; however, AMD has been reported to provoke pulmonary fibrosis (PF) and …

Acute amiodarone pulmonary toxicity

ET Feduska, BN Thoma, MC Torjman… - … of Cardiothoracic and …, 2021 - Elsevier
Amiodarone is an effective antiarrhythmic that frequently is used during the perioperative
period. Amiodarone possesses a significant adverse reaction profile. Amiodarone-induced …

Suppressing NLRP3 activation and PI3K/AKT/mTOR signaling ameliorates amiodarone-induced pulmonary fibrosis in rats: a possible protective role of nobiletin

MM El Tabaa, MM El Tabaa, RM Elgharabawy… - …, 2023 - Springer
Amiodarone (AMD), a medicine used to treat life-threatening arrhythmias, is frequently
linked to pulmonary fibrosis (PF). Despite the involvement of NLRP3 inflammasome and …

Use of 3D human liver organoids to predict drug-induced phospholipidosis

JY Lee, HJ Han, SJ Lee, EH Cho, HB Lee… - International Journal of …, 2020 - mdpi.com
Drug-induced phospholipidosis (PL) is a storage disorder caused by the formation of
phospholipid-drug complexes in lysosomes. Because of the diversity of PL between species …

The inhibitory mechanisms of losartan and vitamin D on amiodarone‐induced lung inflammation in rats: Role of mitogen‐activated protein kinases/activator protein‐1

S Al‐Hassan, H Attia, H Alomar… - Journal of Biochemical …, 2021 - Wiley Online Library
Amiodarone (AMD), an antiarrhythmic drug, is used cautiously due to its lung toxicity that is
characterized by alveolar inflammation followed by fatal fibrosis. AMD induces lung …

Adipose tissue–derived mesenchymal stem cells protect against amiodarone-induced lung injury in rats

SM Radwan, D Ghoneim, M Salem, M Saeed… - Applied Biochemistry …, 2020 - Springer
Pulmonary fibrosis (PF) is a progressive and irreversible lung disease, characterized by
poor prognosis with limited treatment options. Mesenchymal stem cells (MSCs) are multi …

[HTML][HTML] MPoMA protects against lung epithelial cell injury via p65 degradation

S Lee, SJ Yoon, JH Oh, JS Ryu, Y Park… - Biomedicine & …, 2024 - Elsevier
Numerous cases of lung injury caused by viral infection were reported during the
coronavirus disease-19 pandemic. While there have been significant efforts to develop …