Type 2 immunity is orchestrated by a canonical group of cytokines primarily produced by
innate lymphoid cells, group 2, and their adaptive counterparts, CD4+ helper type 2 cells …

Eosinophils are bone marrow‐derived granulocytes and are found in low numbers in the
peripheral blood of healthy subjects. In type 2 inflammatory diseases, eosinopoiesis in the …

Eosinophils are typically considered tissue-damaging effector cells in type 2 immune-related
diseases. However, they are also increasingly recognized as important modulators of …

Eosinophils are a class of granulocytes with pleiotropic functions in homeostasis and
various human diseases. Nevertheless, they are absent from conventional single-cell RNA …

Our understanding of allergic contact dermatitis mechanisms has progressed over the past
decade. Innate immune cells that are involved in the pathogenesis of allergic contact …

Granulocytes provide a fast innate response to pathogens and allergens. In allergy and anti‐
helminth immunity, epithelial cells of damaged barriers release alarmins like IL‐25, IL‐33 …

Basophils bind IgE via FcεRI-αβγ 2, which they uniquely share only with mast cells. In doing
so, they can rapidly release mediators that are hallmark of allergic disease. This …

Periodontitis affects billions of people worldwide. To address relationships of periodontal
niche cell types and microbes in periodontitis, we generated an integrated single-cell RNA …

Obesity incidence is increasing worldwide with the urgent need to identify new therapeutics.
Sex differences in immune cell activation drive obesity-mediated pathologies where males …

Eosinophils are well recognized as effector cells of type 2 immunity, yet they also
accumulate in many tissues under homeostatic conditions. However, the processes that …