Basophils are the least common granulocytes, accounting for< 1% of peripheral blood
leukocytes. In the last 20 years, analytical tools for mouse basophils have been developed …

This review provides an overview of evidence supporting the existence of distinct
homeostatic and inflammatory eosinophil subpopulations in health and disease. Particular …

The murine helminth parasite Heligmosomoides polygyrus expresses a family of modular
proteins which, replicating the functional activity of the immunomodulatory cytokine TGF-β …

Background A role for eosinophils in intestinal inflammation and fibrosis in the context of
inflammatory bowel disease has been suggested, yet the precise nature, whether causal or …

Abstract (50 words) Metabolism shapes immune homeostasis in health and disease. This
review presents the range of methods that are currently available to investigate the dialog …

hydroxytryptamine (5-HT) exerts various physiological effects on the intestine through
different signaling pathways and molecular transmission mechanisms, including pro-and …

This study uncovers the novel heterogeneity of FOXP3+ regulatory T (Treg) cells and their
pivotal role in modulating immune responses during drug-induced allergic reactions …

Eosinophils are a critical type of immune cell and central players in type 2 immunity. Existing
literature suggests that eosinophils also can play a role in host antiviral responses, typically …

The nexus between eosinophils and microbes is attracting increasing attention. We
previously showed that airway administration of sterile microbial products contained in dust …

Memory CD8+ T cell generation is crucial for pathogen elimination and effective vaccination
against infection. The cellular and molecular circuitry that underlies the generation of …