COVID-19 and oxidative stress

BV Chernyak, EN Popova, AS Prikhodko… - Biochemistry …, 2020 - Springer
Pathogenesis of the novel coronavirus infection COVID-19 is the subject of active research
around the world. COVID-19 caused by the SARS-CoV-2 is a complex disease in which …

Endothelial cell dysfunction and the pathobiology of atherosclerosis

MA Gimbrone Jr, G García-Cardeña - Circulation research, 2016 - Am Heart Assoc
Dysfunction of the endothelial lining of lesion-prone areas of the arterial vasculature is an
important contributor to the pathobiology of atherosclerotic cardiovascular disease …

Expert recommendations on the assessment of wall shear stress in human coronary arteries: existing methodologies, technical considerations, and clinical …

F Gijsen, Y Katagiri, P Barlis, C Bourantas… - European heart …, 2019 - academic.oup.com
Expert recommendations on the assessment of wall shear stress in human coronary arteries:
existing methodologies, technical considerations, and clinical applications | European Heart …

Flow-induced reprogramming of endothelial cells in atherosclerosis

IA Tamargo, KI Baek, Y Kim, C Park, H Jo - Nature Reviews Cardiology, 2023 - nature.com
Atherosclerotic diseases such as myocardial infarction, ischaemic stroke and peripheral
artery disease continue to be leading causes of death worldwide despite the success of …

Effects of shear stress on endothelial cells: go with the flow

DA Chistiakov, AN Orekhov, YV Bobryshev - Acta physiologica, 2017 - Wiley Online Library
Haemodynamic forces influence the functional properties of vascular endothelium.
Endothelial cells (ECs) have a variety of receptors, which sense flow and transmit …

Biomechanical factors in atherosclerosis: mechanisms and clinical implications

BR Kwak, M Bäck, ML Bochaton-Piallat… - European heart …, 2014 - academic.oup.com
Blood vessels are exposed to multiple mechanical forces that are exerted on the vessel wall
(radial, circumferential and longitudinal forces) or on the endothelial surface (shear stress) …

Effects of disturbed flow on vascular endothelium: pathophysiological basis and clinical perspectives

JJ Chiu, S Chien - Physiological reviews, 2011 - journals.physiology.org
Vascular endothelial cells (ECs) are exposed to hemodynamic forces, which modulate EC
functions and vascular biology/pathobiology in health and disease. The flow patterns and …

Endothelial shear stress signal transduction and atherogenesis: from mechanisms to therapeutics

L He, CL Zhang, Q Chen, L Wang, Y Huang - Pharmacology & therapeutics, 2022 - Elsevier
Atherosclerotic vascular disease and its complications are among the top causes of mortality
worldwide. In the vascular lumen, atherosclerotic plaques are not randomly distributed …

Molecular biology of atherosclerosis

PN Hopkins - Physiological reviews, 2013 - journals.physiology.org
At least 468 individual genes have been manipulated by molecular methods to study their
effects on the initiation, promotion, and progression of atherosclerosis. Most clinicians and …

The role of Nrf2 in cardiovascular function and disease

S Satta, AM Mahmoud, FL Wilkinson… - Oxidative medicine …, 2017 - Wiley Online Library
Free radicals, reactive oxygen/nitrogen species (ROS/RNS), hydrogen sulphide, and
hydrogen peroxide play an important role in both intracellular and intercellular signaling; …