Crystal engineering of pharmaceutical cocrystals in the discovery and development of improved drugs
The subject of crystal engineering started in the 1970s with the study of topochemical
reactions in the solid state. A broad chemical definition of crystal engineering was published …
reactions in the solid state. A broad chemical definition of crystal engineering was published …
Technological innovations in photochemistry for organic synthesis: flow chemistry, high-throughput experimentation, scale-up, and photoelectrochemistry
L Buglioni, F Raymenants, A Slattery… - Chemical …, 2021 - ACS Publications
Photoinduced chemical transformations have received in recent years a tremendous amount
of attention, providing a plethora of opportunities to synthetic organic chemists. However …
of attention, providing a plethora of opportunities to synthetic organic chemists. However …
Bayesian Self‐Optimization for Telescoped Continuous Flow Synthesis
AD Clayton, EO Pyzer‐Knapp, M Purdie… - Angewandte …, 2023 - Wiley Online Library
The optimization of multistep chemical syntheses is critical for the rapid development of new
pharmaceuticals. However, concatenating individually optimized reactions can lead to …
pharmaceuticals. However, concatenating individually optimized reactions can lead to …
Protein‐based Nanoparticles: from Drug Delivery to Imaging, Nanocatalysis and Protein Therapy
J Kaltbeitzel, PR Wich - Angewandte Chemie International …, 2023 - Wiley Online Library
Proteins and enzymes are versatile biomaterials for a wide range of medical applications
due to their high specificity for receptors and substrates, high degradability, low toxicity, and …
due to their high specificity for receptors and substrates, high degradability, low toxicity, and …
Towards 4th industrial revolution efficient and sustainable continuous flow manufacturing of active pharmaceutical ingredients
CR Sagandira, S Nqeketo, K Mhlana, T Sonti… - Reaction Chemistry & …, 2022 - pubs.rsc.org
Continuous flow chemistry has opened a new paradigm in both the laboratory and
pharmaceutical industry. This review details the recently reported literature on continuous …
pharmaceutical industry. This review details the recently reported literature on continuous …
Multiphasic Continuous‐Flow Reactors for Handling Gaseous Reagents in Organic Synthesis: Enhancing Efficiency and Safety in Chemical Processes
The use of reactive gaseous reagents for the production of active pharmaceutical
ingredients (APIs) remains a scientific challenge due to safety and efficiency limitations. The …
ingredients (APIs) remains a scientific challenge due to safety and efficiency limitations. The …
Process analytical technologies and self-optimization algorithms in automated pharmaceutical continuous manufacturing
P Liu, H Jin, Y Chen, D Wang, H Yan, M Wu… - Chinese Chemical …, 2023 - Elsevier
The pharmaceutical industry is now paying increased attention to continuous manufacturing.
While the revolution to continuous and automated manufacturing is deepening in most of the …
While the revolution to continuous and automated manufacturing is deepening in most of the …
[HTML][HTML] Synergy of visible-light responsive photocatalytic materials and device engineering for energy and environment: Minireview on hydrogen production and …
P Jiménez-Calvo - Materials Today Catalysis, 2024 - Elsevier
Accelerated advances in photocatalysis demand alignment with a well-defined Technology
Readiness Levels (TRLs) roadmap to overcome bottlenecks and attain TRLs of 3 or beyond …
Readiness Levels (TRLs) roadmap to overcome bottlenecks and attain TRLs of 3 or beyond …
Continuous Flow Chemistry with Solids: A Review
HLD Hayes, CJ Mallia - Organic Process Research & …, 2024 - ACS Publications
The effective handling of solids in a continuous flow process is one of the biggest perceived
challenges remaining for modern flow chemistry. This Review aims to consider some of the …
challenges remaining for modern flow chemistry. This Review aims to consider some of the …
Tackling current production of HAp and HAp-driven biomaterials
A Veiga, S Madureira, JB Costa, F Castro… - Materials …, 2023 - pubs.rsc.org
Hydroxyapatite (HAp)-based biomaterials are well-established for biomedical applications
due to their extensive research work and clinical track record. Recent efforts have been …
due to their extensive research work and clinical track record. Recent efforts have been …