Translocated in liposarcoma, Ewing's sarcoma and TATA-binding protein-associated factor
15 constitute an interesting and important family of proteins known as the TET proteins. The …

Misfolded TAR DNA binding protein 43 (TDP-43) and Fused-In-Sarcoma (FUS) protein have
recently been identified as pathological hallmarks of the neurodegenerative disorders …

Neuronal dendrites, together with dendritic spines, exhibit enormously diverse structure [1].
Selective targeting and local translation of mRNAs in dendritic spines have been implicated …

C2H2 (Cys-Cys-His-His motif) zinc finger proteins are members of a large superfamily of
nucleic-acid-binding proteins in eukaryotes. On the basis of NMR and X-ray structures, we …

microRNA abundance has been shown to depend on the amount of the microprocessor
components or, in some cases, on specific auxiliary co‐factors. In this paper, we show that …

Stress granules (SG s) are cytoplasmic foci that rapidly form when cells are exposed to
stress. They transiently store m RNA s encoding house‐keeping proteins and allow the …

526-residue Fused in sarcoma (FUS) undergoes liquid–liquid phase separation (LLPS) for
its functions, which can further transit into pathological aggregation. ATP and nucleic acids …

FUS, a nuclear RNA-binding protein, plays multiple roles in RNA processing. Five specific
FUS-binding RNA sequence/structure motifs have been proposed, but their affinities for FUS …

TLS (translocation in liposarcoma), an RNA-binding protein, was originally identified as a
heterogeneous ribonuclear protein (hnRNP). Recently, we showed that TLS is localized in …

Amyotrophic lateral sclerosis (ALS), a common motor neuron disease affecting two per
100,000 people worldwide, encompasses at least five distinct pathological subtypes …