miRNAs as biomarkers in disease: latest findings regarding their role in diagnosis and prognosis
CE Condrat, DC Thompson, MG Barbu, OL Bugnar… - Cells, 2020 - mdpi.com
MicroRNAs (miRNAs) represent a class of small, non-coding RNAs with the main roles of
regulating mRNA through its degradation and adjusting protein levels. In recent years …
regulating mRNA through its degradation and adjusting protein levels. In recent years …
Dietary regulation in health and disease
Nutriments have been deemed to impact all physiopathologic processes. Recent evidences
in molecular medicine and clinical trials have demonstrated that adequate nutrition …
in molecular medicine and clinical trials have demonstrated that adequate nutrition …
Role of exosomes in central nervous system diseases
W Liu, X Bai, A Zhang, J Huang, S Xu… - Frontiers in molecular …, 2019 - frontiersin.org
There are many types of intercellular communication, and extracellular vesicles are one of
the important forms of this. They are released by a variety of cell types, are heterogeneous …
the important forms of this. They are released by a variety of cell types, are heterogeneous …
The evolving landscape of exosomes in neurodegenerative diseases: exosomes characteristics and a promising role in early diagnosis
S Rastogi, V Sharma, PS Bharti, K Rani… - International journal of …, 2021 - mdpi.com
Neurodegenerative diseases (ND) remains to be one of the biggest burdens on healthcare
systems and serves as a leading cause of disability and death. Alzheimer's disease (AD) is …
systems and serves as a leading cause of disability and death. Alzheimer's disease (AD) is …
Oxidative stress, aging, antioxidant supplementation and their impact on human health: An overview
G Martemucci, P Portincasa, A Di Ciaula… - Mechanisms of Ageing …, 2022 - Elsevier
Aging is characterized by a progressive loss of tissue and organ function due to genetic and
environmental factors, nutrition, and lifestyle. Oxidative stress is one the most important …
environmental factors, nutrition, and lifestyle. Oxidative stress is one the most important …
MicroRNAs as modulators of longevity and the aging process
HE Kinser, Z Pincus - Human genetics, 2020 - Springer
MicroRNAs (miRNAs) are short, non-coding RNAs that post-transcriptionally repress
translation or induce mRNA degradation of target transcripts through sequence-specific …
translation or induce mRNA degradation of target transcripts through sequence-specific …
Blood-based biomarkers for Alzheimer's disease diagnosis and progression: an overview
A Varesi, A Carrara, VG Pires, V Floris, E Pierella… - Cells, 2022 - mdpi.com
Alzheimer's Disease (AD) is a progressive neurodegenerative disease characterized by
amyloid-β (Aβ) plaque deposition and neurofibrillary tangle accumulation in the brain …
amyloid-β (Aβ) plaque deposition and neurofibrillary tangle accumulation in the brain …
Circulating brain-enriched microRNAs as novel biomarkers for detection and differentiation of neurodegenerative diseases
KS Sheinerman, JB Toledo, VG Tsivinsky… - Alzheimer's research & …, 2017 - Springer
Background Minimally invasive specific biomarkers of neurodegenerative diseases (NDs)
would facilitate patient selection and disease progression monitoring. We describe the …
would facilitate patient selection and disease progression monitoring. We describe the …
[HTML][HTML] The early-life exposome and epigenetic age acceleration in children
P de Prado-Bert, C Ruiz-Arenas, M Vives-Usano… - Environment …, 2021 - Elsevier
The early-life exposome influences future health and accelerated biological aging has been
proposed as one of the underlying biological mechanisms. We investigated the association …
proposed as one of the underlying biological mechanisms. We investigated the association …
MicroRNAs dysregulation and mitochondrial dysfunction in neurodegenerative diseases
M Catanesi, M d'Angelo, MG Tupone… - International Journal of …, 2020 - mdpi.com
Neurodegenerative diseases are debilitating and currently incurable conditions causing
severe cognitive and motor impairments, defined by the progressive deterioration of …
severe cognitive and motor impairments, defined by the progressive deterioration of …