Congenital heart disease (CHD) affects~ 1% of all live births, but a definitive etiology is
identified in only~ 50%. The causes include chromosomal aneuploidies and copy-number …

Genomic copy-number variants (CNVs) contribute to as many congenital heart disease
(CHD) cases (10–15%) as chromosomal aberrations or single-gene mutations and influence …

Placental abnormalities have been sporadically implicated as a source of developmental
heart defects. Yet it remains unknown how often the placenta is at the root of congenital …

Background Dilated cardiomyopathy (DCM), characterized by progressive left ventricular
enlargement and systolic dysfunction, is the most common type of cardiomyopathy and a …

Chronic kidney disease (CKD) is an increasing health care problem. About 10% of the
general population is affected by CKD, representing the sixth cause of death in the world …

These new insights into the genetic contributors of AVD have offered new avenues for
translational disease investigation, bridging molecular discoveries to emergent …

Background Pathogenic GATA6 variants have been associated with congenital heart
disease (CHD) and a spectrum of extracardiac abnormalities, including pancreatic agenesis …

Background Congenital heart disease (CHD) is a severe childhood health problem
worldwide. This study analyzes the scientific production on CHD published in Scopus during …

As the most common form of developmental malformation affecting the heart and
endothoracic great vessels, congenital heart disease (CHD) confers substantial morbidity …

Syndromic birth defects are rare diseases that can present with seemingly pleiotropic
comorbidities. Prime examples are rare congenital heart and cardiovascular anomalies that …