The clinical pharmacogenetics implementation consortium: 10 years later
In 2009, the Clinical Pharmacogenetics Implementation Consortium (CPIC, www. cpicpgx.
org), a shared project between Pharmacogenomics Knowledge Base (PharmGKB …
org), a shared project between Pharmacogenomics Knowledge Base (PharmGKB …
Translating pharmacogenomics into clinical decisions: do not let the perfect be the enemy of the good
K Krebs, L Milani - Human genomics, 2019 - Springer
The field of pharmacogenomics (PGx) is gradually shifting from the reactive testing of single
genes toward the proactive testing of multiple genes to improve treatment outcomes, reduce …
genes toward the proactive testing of multiple genes to improve treatment outcomes, reduce …
Standardizing CYP2D6 Genotype to Phenotype Translation: Consensus Recommendations from the Clinical Pharmacogenetics Implementation Consortium and …
KE Caudle, K Sangkuhl, M Whirl‐Carrillo… - Clinical and …, 2020 - Wiley Online Library
Translating CYP 2D6 genotype to metabolizer phenotype is not standardized across clinical
laboratories offering pharmacogenetic (PGx) testing and PGx clinical practice guidelines …
laboratories offering pharmacogenetic (PGx) testing and PGx clinical practice guidelines …
[HTML][HTML] Recommendations for clinical CYP2D6 genotyping allele selection: a joint consensus recommendation of the Association for Molecular Pathology, College of …
VM Pratt, LH Cavallari, AL Del Tredici… - The Journal of Molecular …, 2021 - Elsevier
The goals of the Association for Molecular Pathology Clinical Practice Committee's
Pharmacogenomics (PGx) Working Group are to define the key attributes of …
Pharmacogenomics (PGx) Working Group are to define the key attributes of …
Genophenotypic factors and pharmacogenomics in adverse drug reactions
R Cacabelos, V Naidoo, L Corzo, N Cacabelos… - International journal of …, 2021 - mdpi.com
Adverse drug reactions (ADRs) rank as one of the top 10 leading causes of death and
illness in developed countries. ADRs show differential features depending upon genotype …
illness in developed countries. ADRs show differential features depending upon genotype …
Barriers to clinical adoption of pharmacogenomic testing in psychiatry: a critical analysis
CR Virelli, AG Mohiuddin, JL Kennedy - Translational psychiatry, 2021 - nature.com
Pharmacogenomics (PGx) is the study of genetic influences on an individual's response to
medications. Improvements in the quality and quantity of PGx research over the past two …
medications. Improvements in the quality and quantity of PGx research over the past two …
ASHP statement on the pharmacist's role in clinical pharmacogenomics
Background Clinical pharmacogenomics uses genetic information to guide optimal drug
selection and drug dosing for patients to maximize therapeutic effects, improve outcomes …
selection and drug dosing for patients to maximize therapeutic effects, improve outcomes …
Development of the PG x‐Passport: a panel of actionable germline genetic variants for pre‐emptive pharmacogenetic testing
CH van der Wouden, MH van Rhenen… - Clinical …, 2019 - Wiley Online Library
Pre‐emptive pharmacogenetics (PG x) testing of a panel of germline genetic variants
represents a new model for personalized medicine. Clinical impact of PG x testing is …
represents a new model for personalized medicine. Clinical impact of PG x testing is …
Moving pharmacogenetics into practice: it's all about the evidence!
The evidence for pharmacogenetics has grown rapidly in recent decades. However, the
strength of evidence required for the clinical implementation of pharmacogenetics is highly …
strength of evidence required for the clinical implementation of pharmacogenetics is highly …
Advancing pharmacogenomics from single-gene to preemptive testing
Pharmacogenomic testing can be an effective tool to enhance medication safety and
efficacy. Pharmacogenomically actionable medications are widely used, and approximately …
efficacy. Pharmacogenomically actionable medications are widely used, and approximately …