Recent progress of interferon-tau research and potential direction beyond pregnancy recognition
H Bai, M Kawahara, M Takahashi… - Journal of Reproduction …, 2022 - jstage.jst.go.jp
Since the discovery of interferon-tau (IFNT) over 30 years ago as the trophectodermal
cytokine responsible for the maintenance of the maternal corpus luteum (CL) in ruminants …
cytokine responsible for the maintenance of the maternal corpus luteum (CL) in ruminants …
[HTML][HTML] Effects of miR-98 in intrauterine extracellular vesicles on maternal immune regulation during the peri-implantation period in cattle
K Nakamura, K Kusama, A Ideta, K Kimura, M Hori… - Scientific reports, 2019 - nature.com
Evidence accumulated suggests that extracellular vesicles (EVs) present in uterine lumen
play a role in conceptus-endometrial cell interactions during peri-implantation periods …
play a role in conceptus-endometrial cell interactions during peri-implantation periods …
Intrauterine exosomes are required for bovine conceptus implantation
K Kusama, K Nakamura, R Bai, K Nagaoka… - Biochemical and …, 2018 - Elsevier
Exosomes, extracellular vesicles, are present in uterine flushing fluids (UFs), which are
involved in conceptus-endometrial interactions during peri-implantation periods. Despite …
involved in conceptus-endometrial interactions during peri-implantation periods. Despite …
Human endometrial transcriptome and progesterone receptor cistrome reveal important pathways and epithelial regulators
Context Poor uterine receptivity is one major factor leading to pregnancy loss and infertility.
Understanding the molecular events governing successful implantation is hence critical in …
Understanding the molecular events governing successful implantation is hence critical in …
Transforming growth factor-β superfamily and interferon-τ in ovarian function and embryo development in female cattle: review of biology and application
JD Michael, G Campanile… - Reproduction, Fertility and …, 2020 - CSIRO Publishing
Survival of the embryo and establishment of a pregnancy is a critical period in the
reproductive function of female cattle. This review examines how the transforming growth …
reproductive function of female cattle. This review examines how the transforming growth …
Induction of immune-related gene expression by seminal exosomes in the porcine endometrium
R Bai, Z Latifi, K Kusama, K Nakamura… - Biochemical and …, 2018 - Elsevier
Seminal plasma (SP) is considered as a vehicle to carry sperm into female reproductive
tract, of which functions have not been completely understood. This study aimed to identify …
tract, of which functions have not been completely understood. This study aimed to identify …
The effect of bta-miR-26b in intrauterine extracellular vesicles on maternal immune system during the implantation period
K Nakamura, K Kusama, M Hori, K Imakawa - Biochemical and Biophysical …, 2021 - Elsevier
Extracellular vesicles (EVs) in utero play a role in cellular interactions between endometrium-
conceptuses (embryo plus extraembryonic membranes) during peri-implantation periods …
conceptuses (embryo plus extraembryonic membranes) during peri-implantation periods …
IFNT-independent effects of intrauterine extracellular vesicles (EVs) in cattle
K Nakamura, K Kusama, A Ideta, K Imakawa… - …, 2020 - rep.bioscientifica.com
Extracellular vesicles (EVs) present in uterine lumen are involved in conceptus-endometrial
interactions during the pre-implantation period. Despite numerous studies conducted on …
interactions during the pre-implantation period. Despite numerous studies conducted on …
[HTML][HTML] Analysis and screening of reproductive long non-coding RNAs through genome-wide analyses of goat endometrium during the pre-attachment phase
L Hong, Q Hu, X Zang, Y Xie, C Zhou, X Zou, Y Li… - Frontiers in …, 2020 - frontiersin.org
Reproduction in goat is highly impeded by implantation failure. Of concern, the underlying
mechanism leading to embryo implantation remains unclear. In this study, deep sequencing …
mechanism leading to embryo implantation remains unclear. In this study, deep sequencing …
Regulation of human trophoblast cell syncytialization by transcription factors STAT5B and NR4A3
K Kusama, R Bai, K Imakawa - Journal of Cellular Biochemistry, 2018 - Wiley Online Library
In human trophoblast cells, cyclic AMP or its inducer forskolin (FSK) activates two
downstream signaling molecules, protein kinase A (PKA) and exchange protein directly …
downstream signaling molecules, protein kinase A (PKA) and exchange protein directly …