Comparison between the Biological Active Compounds in Plants with Adaptogenic Properties (Rhaponticum carthamoides, Lepidium meyenii, Eleutherococcus senticosus and …

V Todorova, K Ivanov, S Ivanova - Plants, 2021 - mdpi.com
Background: In the 1960s, research into plant adaptogens began. Plants with adaptogenic
properties have rich phytochemical compositions and have been used by humanity since …

Anti-Neuroinflammatory Effects of Adaptogens: A Mini-Review

D Wróbel-Biedrawa, I Podolak - Molecules, 2024 - mdpi.com
Introduction: Adaptogens are a group of plants that exhibit complex, nonspecific effects on
the human body, increasing its ability to adapt, develop resilience, and survive in stress …

CLC-Pred 2.0: a freely available web application for in silico prediction of human cell line cytotoxicity and molecular mechanisms of action for druglike compounds

AA Lagunin, AV Rudik, PV Pogodin… - International Journal of …, 2023 - mdpi.com
In vitro cell-line cytotoxicity is widely used in the experimental studies of potential
antineoplastic agents and evaluation of safety in drug discovery. In silico estimation of …

Alternative experimental approaches to reduce animal use in biomedical studies

SY Lee, JH Kang, JW Jeong, JH Kim, HW Kim… - Journal of Drug Delivery …, 2022 - Elsevier
We review experimental approaches that can be used instead of in vivo studies involving
vertebrate animal models and human clinical trials. The existing alternative experimental …

[HTML][HTML] Tea saponin additive to extract eleutheroside B and E from Eleutherococcus senticosus by ultrasonic mediation and its application in a semi-pilot scale

X Yang, T Liu, S Qi, H Gu, J Li, L Yang - Ultrasonics sonochemistry, 2022 - Elsevier
The safety of ethanol in operations and its effects on human health are gradually being
questioned. Under this premise, we attempted to use the natural surfactant tea saponin …

The Therapeutic Effect of Acanthopanax senticosus Components on Radiation-Induced Brain Injury Based on the Pharmacokinetics and Neurotransmitters

C Song, S Li, F Duan, M Liu, S Shan, T Ju, Y Zhang… - Molecules, 2022 - mdpi.com
Acanthopanax senticosus (AS) is a medicinal and food homologous plant with many
biological activities. In this research, we generated a brain injury model by 60Co-γ ray …

Potential herb–drug interactions in the management of age-related cognitive dysfunction

MD Auxtero, S Chalante, MR Abade, R Jorge… - Pharmaceutics, 2021 - mdpi.com
Late-life mild cognitive impairment and dementia represent a significant burden on
healthcare systems and a unique challenge to medicine due to the currently limited …

Non-targeted characteristic filter analysis combined with in silico prediction strategies to identify the chemical components and in vivo metabolites of Dalitong Granules …

Y Su, L Tao, X Zhang, X Sheng, Q Li, W Fei… - … of Pharmaceutical and …, 2023 - Elsevier
Dalitong Granules, a potent gastrointestinal motility promoting traditional Chinese medicine,
is used to treat functional dyspepsia clinically. It shows good effect on alleviating …

The standardization of officinal medicinal plants used in the Eurasian Economic Union: Comparison with other pharmacopoeias

AO Whaley, AK Whaley, EL Kovaleva, LN Frolova… - Phytochemistry …, 2024 - Springer
Pharmacopoeias are important resources for the quality control of medicinal plants and their
products. Considering that approximately 80% of the world population to different extents …

ADMET profiling and molecular docking of potential antimicrobial peptides previously isolated from African catfish, Clarias gariepinus

H Okella, E Okello, AG Mtewa, H Ikiriza… - Frontiers in Molecular …, 2022 - frontiersin.org
Amidst rising cases of antimicrobial resistance, antimicrobial peptides (AMPs) are regarded
as a promising alternative to traditional antibiotics. Even so, poor pharmacokinetic profiles of …