Porphyromonas gingivalis is strongly correlated with chronic periodontitis. Its chronic
persistence in the periodontium depends on its ability to evade host immunity without …

Atherosclerosis (AS), one of the most common types of cardiovascular disease, has initially
been attributed to the accumulation of fats and fibrous materials. However, more and more …

Abstract Purpose of Review This review summarizes mechanisms by which Porphyromonas
gingivalis interacts with community members and the host so that it can persist in the …

Signaling crosstalk between complement and Toll-like receptors (TLRs) normally serves to
coordinate host immunity. However, the periodontal bacterium Porphyromonas gingivalis …

Simple Summary Periodontal disease and atherosclerotic cardiovascular disease are very
common around the world. Coronary artery disease is the leading cause of death. The main …

Although the complement system is centrally involved in host defense, its overactivation or
deregulation (eg, due to inherent host genetic defects or due to pathogen subversion) may …

CD36 participates in macrophage internalization of a variety of particles, and has been
implicated in inflammatory responses to many of these ligands. To what extent CD36 …

The ability of certain pathogens to exploit innate immune function allows them to undermine
immune clearance and thereby increase their persistence and capacity to cause disease …

Mucosal tissues act as a barrier throughout the oral, nasopharyngeal, lung, and intestinal
systems, offering first-line protection against potential pathogens. Conventionally, vaccines …

Porphyromonas gingivalis is considered a major pathogen in adult periodontitis and is also
associated with multiple systemic diseases, for example, cardiovascular diseases. One of its …