Oxidative stress: a suitable therapeutic target for optic nerve diseases?

F Buonfiglio, EW Böhm, N Pfeiffer, A Gericke - Antioxidants, 2023 - mdpi.com
Optic nerve disorders encompass a wide spectrum of conditions characterized by the loss of
retinal ganglion cells (RGCs) and subsequent degeneration of the optic nerve. The etiology …

Vitamins in neuropathy: Pathophysiological and therapeutic roles

P Chen, XJ Song - Current Opinion in Neurology, 2023 - journals.lww.com
The vitamins play critical roles in maintaining physiological functions, and vitamin
deficiencies cause peripheral neuropathy with various severe and complex diseases. The …

[HTML][HTML] Rapid and sensitive diagnosis of Leber hereditary optic neuropathy variants using CRISPR/Cas12a detection

X Wan, J Chen, Y Wu, Z Chen, Y Liu, T Li, J Sun… - The Journal of Molecular …, 2023 - Elsevier
Leber hereditary optic neuropathy (LHON) is the most common maternally inherited
mitochondrial disease, with> 90% of cases harboring one of three point variants (m. 3460G> …

The Optic Nerve at Stake: Update on Environmental Factors Modulating Expression of Leber's Hereditary Optic Neuropathy

P Layrolle, C Orssaud, M Leleu, P Payoux, S Chavanas - Biomedicines, 2024 - mdpi.com
Optic neuropathies are characterized by the degeneration of the optic nerves and represent
a considerable individual and societal burden. Notably, Leber's hereditary optic neuropathy …

Nutritional factors: benefits in glaucoma and ophthalmologic pathologies

M Musa, M Zeppieri, GN Atuanya, ES Enaholo… - Life, 2023 - mdpi.com
Glaucoma is a chronic optic neuropathy that can lead to irreversible functional and
morphological damage if left untreated. The gold standard therapeutic approaches in …

Leber's hereditary optic neuropathy: Update on current diagnosis and treatment

A Esmaeil, A Ali, R Behbehani - Frontiers in Ophthalmology, 2023 - frontiersin.org
Leber's hereditary optic neuropathy (LHON) is a fairly prevalent mitochondrial disorder (1:
50,000) arising from the dysfunction of the mitochondrial respiratory chain, which eventually …

Before an abducens palsy can be attributed to a congenital vitamin-B12 deficiency, alternative causes must be ruled out

J Finsterer - Child's Nervous System, 2023 - Springer
We read with interest the article by Krishna et al. who reported on a 1-year-old male
diagnosed with bilateral abducens palsy secondary to congenital dietary vitamin-B12 …

Live Microstructural Analysis of Rare Eye Diseases with Modern Technologies

MR Boyadzhieva - 2023 - search.proquest.com
Rare diseases (RD) are a heterogeneous group of diseases defined as pathological
conditions with low incidence and morbidity. More than 7,000 rare diseases are known, of …

[PDF][PDF] Nutrients for Eye Health and Disease Management

J Khadamy - researchgate.net
The intricate link between nutrition and ocular well-being is garnering significant attention
within the field of ophthalmology. This comprehensive review explores the pivotal role of …