Iron deficiency and cardiovascular disease

G Savarese, S von Haehling, J Butler… - European heart …, 2023 - academic.oup.com
Iron deficiency (ID) is common in patients with cardiovascular disease. Up to 60% of patients
with coronary artery disease, and an even higher proportion of those with heart failure (HF) …

2022 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension: Developed by the task force for the diagnosis and treatment of pulmonary …

M Humbert, G Kovacs, MM Hoeper… - European heart …, 2022 - academic.oup.com
Pulmonary hypertension (PH) is a pathophysiological disorder that may involve multiple
clinical conditions and may be associated with a variety of cardiovascular and respiratory …

2022 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension

M Humbert, G Kovacs, MM Hoeper… - European …, 2023 - Eur Respiratory Soc
Guidelines summarize and evaluate available evidence, with the aim of assisting health
professionals in proposing the best management strategies for an individual patient with a …

Serum iron level as a potential predictor of coronavirus disease 2019 severity and mortality: a retrospective study

K Zhao, J Huang, D Dai, Y Feng, L Liu… - Open forum infectious …, 2020 - academic.oup.com
Background Various types of pulmonary diseases are associated with iron deficiency.
However, information on iron status in coronavirus disease 2019 (COVID-19) is scarce …

Systemic consequences of pulmonary hypertension and right-sided heart failure

S Rosenkranz, LS Howard, M Gomberg-Maitland… - Circulation, 2020 - Am Heart Assoc
Pulmonary hypertension (PH) is a feature of a variety of diseases and continues to harbor
high morbidity and mortality. The main consequence of PH is right-sided heart failure which …

Clinical trial design and new therapies for pulmonary arterial hypertension

O Sitbon, M Gomberg-Maitland… - European …, 2019 - Eur Respiratory Soc
Until 20 years ago the treatment of pulmonary arterial hypertension (PAH) was based on
case reports and small series, and was largely ineffectual. As a deeper understanding of the …

Current and future treatments of pulmonary arterial hypertension

N Sommer, HA Ghofrani, O Pak… - British journal of …, 2021 - Wiley Online Library
Therapeutic options for pulmonary arterial hypertension (PAH) have increased over the last
decades. The advent of pharmacological therapies targeting the prostacyclin, endothelin …

[HTML][HTML] Mitochondrial metabolism in pulmonary hypertension: beyond mountains there are mountains

MK Culley, SY Chan - The Journal of clinical investigation, 2018 - Am Soc Clin Investig
Pulmonary hypertension (PH) is a heterogeneous and fatal disease of the lung vasculature,
where metabolic and mitochondrial dysfunction may drive pathogenesis. Similar to the …

[HTML][HTML] Molecular mechanisms of pulmonary vascular remodeling in pulmonary arterial hypertension

JA Leopold, BA Maron - International journal of molecular sciences, 2016 - mdpi.com
Pulmonary arterial hypertension (PAH) is a devastating disease that is precipitated by
hypertrophic pulmonary vascular remodeling of distal arterioles to increase pulmonary artery …

[HTML][HTML] Iron in cardiovascular disease: challenges and potentials

S Li, X Zhang - Frontiers in cardiovascular medicine, 2021 - frontiersin.org
Iron is essential for many biological processes. Inadequate or excess amount of body iron
can result in various pathological consequences. The pathological roles of iron in …