Alhagi camelorum (AC) is an old plant with a significant therapeutic value throughout Africa,
Asia, and Latin America. The overuse of cisplatin (Cis> 50 mg/m2) is associated with …

Breast cancer is considered a universal public health dilemma in women. Due to the high
toxicity and low selectivity of conventional anticancer therapies, there is a growing trend of …

The overuse of cisplatin (> 50 mg/m2) is limited to nephrotoxicity, ototoxicity, gastrotoxicity,
myelosuppression, and allergic reactions. The objective of this study was to investigate the …

The aim of the present study was the proposal of a strategy to permit the safe use of the
powerful antitumor agent Cisplatin. Considering the possibility of reducing the oxidative …

Acute kidney injury (AKI) is the main obstacle that limits the use of cisplatin in cancer
treatment. Proton pump inhibitors (PPIs), the most commonly used class of medications for …

Cisplatin is one of the synthetic cancer medicines with nephrotoxicity being one of its major
side effects. Past research shows that calcium dobesilate (CaD), as a vascular protective …

Cisplatin (CP) is commonly used in the treatment of various solid tumors. Its use, however, is
hampered by nephrotoxicity. In this study, we compared the effect of betaine and melatonin …

Cisplatin (CDDP) is one of the most frequently prescribed chemotherapy medications.
However, its nephrotoxicity which often leads to acute kidney injury (AKI), greatly limits its …

Background. Cisplatin is a powerful chemotherapeutic drug mainly used in the treatment of
solid tumors. Aggregation of the drug in renal proximal tubule cells causes nephrotoxicity …

The current study was designed to evaluate the potential abatement effect of pantoprazole
against cisplatin-induced nephrotoxicity and establishing the possible protective …