Human thyroid cancer cell lines are the most used models for thyroid cancer studies. They
must be used with detailed knowledge of their characteristics. These in vitro cell lines …

Publisher Summary This chapter discusses the interaction of human cytomegalovirus
(HCMV) with different host cells in vitro and in vivo. The role of different cell populations in …

Context: Cell lines derived from human cancers provide critical tools to study disease
mechanisms and develop novel therapies. Recent reports indicate that up to 36% of cell …

MicroRNAs (miRNAs) are a class of small non-coding RNAs involved in a wide range of
basic processes such as cell proliferation, development, apoptosis and stress response. It …

We have recently reported that MicroRNAs (miR)-221 and miR-222 were up-regulated in
human thyroid papillary carcinomas in comparison with the normal thyroid tissue …

Micro RNAs (miRNAs) are non‐coding small RNAs and constitute a novel class of negative
gene regulators that are found in both plants and animals. Several miRNAs play crucial …

The insulin receptor (IR) occurs in two isoforms (IR-A and IR-B) resulting from alternative
splicing of exon 11 of the gene. The IR-A isoform is predominantly expressed in fetal tissues …

Although there are a number of excellent current reviews on one or another aspect of
cytomegalovirus, the last comprehensive treatment of this subject was that of Krech et …

We have investigated the role of the NFκB complex in the process of thyroid carcinogenesis
by analysing thyroid carcinoma cell lines. A significant increase in p65 NFκB mRNA and …

Aberrant reactivation of embryonic pathways is a common feature of cancer. RUNX2 is a
transcription factor crucial during embryogenesis that is aberrantly reactivated in many …