Chitosan oligosaccharide–arachidic acid-based nanoparticles for anti-cancer drug delivery

U Termsarasab, HJ Cho, DH Kim, S Chong… - International journal of …, 2013 - Elsevier
Chitosan oligosaccharide–arachidic acid (CSOAA) conjugate was successfully synthesized
and used for the development of self-assembled nanoparticles for doxorubicin (DOX) …

Using microfluidic platforms to develop CNS-targeted polymeric nanoparticles for HIV therapy

C Martins, F Araújo, MJ Gomes, C Fernandes… - European Journal of …, 2019 - Elsevier
The human immunodeficiency virus (HIV) uses the brain as reservoir, which turns it as a
promising target to fight this pathology. Nanoparticles (NPs) of poly (lactic-co-glycolic) acid …

Biopolymers in controlled-release delivery systems

K Pal, AT Paulson, D Rousseau - Modern biopolymer science, 2009 - Elsevier
Publisher Summary The flexibility in polymer processing plays an important role in the
development of controlled delivery devices for a range of applications related to drugs, food …

In vitro hemocompatibility and cytotoxicity evaluation of halloysite nanotubes for biomedical application

HY Liu, L Du, YT Zhao, WQ Tian - Journal of nanomaterials, 2015 - Wiley Online Library
Halloysite nanotubes (HNTs), due to their unique structures and properties, may play an
important role in biomedical applications. In vitro test is usually conducted as a preliminary …

Nanotoxicology: advances and pitfalls in research methodology

M Azhdarzadeh, AA Saei, S Sharifi, MJ Hajipour… - …, 2015 - Taylor & Francis
As research progresses, nanoparticles (NPs) are becoming increasingly promising tools for
medical diagnostics and therapeutics. Despite this rise, their potential risks to human health …

Fracture-Targeted Delivery of β-Catenin Agonists via Peptide-Functionalized Nanoparticles Augments Fracture Healing

Y Wang, MR Newman, M Ackun-Farmmer… - ACS …, 2017 - ACS Publications
Despite several decades of progress, bone-specific drug delivery is still a major challenge.
Current bone-acting drugs require high-dose systemic administration which decreases …

Influence of silica particle internalization on adhesion and migration of human dermal fibroblasts

Y Zhang, L Hu, D Yu, C Gao - Biomaterials, 2010 - Elsevier
In spite of significant advantages exhibiting in the applications of silicon dioxide particles in
biological and medicine fields, their adverse effects still remain a big concern. Herein …

Biotin receptor-targeting nanogels loaded with methotrexate for enhanced antitumor efficacy in triple-negative breast cancer in vitro and in vivo models

SS Abolmaali, S Zarenejad, Y Mohebi, H Najafi… - International Journal of …, 2022 - Elsevier
High-dose methotrexate (MTX) chemotherapeutic applications confront drug specificity and
pharmacokinetic challenges, which can be overcome by utilizing targeted drug delivery …

Quantifying the adsorption and uptake of CuO nanoparticles by wheat root based on chemical extractions

D Zhou, S Jin, L Li, Y Wang, N Weng - Journal of Environmental Sciences, 2011 - Elsevier
Extensive application of metal nanoparticles is attracting more attention because of their
potential environmental risks. Many studies have focused on the uptake of metal …

Nanomedicine: perspective and promises with ligand-directed molecular imaging

D Pan, GM Lanza, SA Wickline, SD Caruthers - European journal of …, 2009 - Elsevier
Molecular imaging and targeted drug delivery play an important role toward personalized
medicine, which is the future of patient management. Of late, nanoparticle-based molecular …