Long non‐coding RNA regulation of reproduction and development

DH Taylor, ETJ Chu, R Spektor… - Molecular reproduction …, 2015 - Wiley Online Library
Noncoding RNAs (ncRNAs) have long been known to play vital roles in eukaryotic gene
regulation. Studies conducted over a decade ago revealed that maturation of spliced …

[PDF][PDF] Actions of gonadotrophins on the uterus

M Shemesh - REPRODUCTION-CAMBRIDGE-, 2001 - academia.edu
Binding sites for LH/hCG are found in the uterus of several species, including humans. In
cattle and pigs, the LH receptor, its mRNA and LH receptor protein are present in the uterus …

[HTML][HTML] Transcriptome dynamics and molecular cross-talk between bovine oocyte and its companion cumulus cells

A Regassa, F Rings, M Hoelker, U Cinar, E Tholen… - BMC genomics, 2011 - Springer
The bi-directional communication between the oocyte and its companion cumulus cells
(CCs) is crucial for development and functions of both cell types. Transcripts that are …

Cumulus cell gene expression following the LH surge in bovine preovulatory follicles: potential early markers of oocyte competence

M Assidi, SJ Dieleman, MA Sirard - Reproduction, 2010 - rep.bioscientifica.com
Cumulus cells (CCs) are essential for oocytes to reach full development competency and
become fertilized. Many major functional properties of CCs are triggered by gonadotropins …

Cytoplasmic glutathione regulated by cumulus cells during porcine oocyte maturation affects fertilization and embryonic development in vitro

N Maedomari, K Kikuchi, M Ozawa, J Noguchi… - Theriogenology, 2007 - Elsevier
It is generally accepted that cumulus cells support the nuclear maturation of mammalian
oocytes. In the present study, we examined relationships between the cytoplasmic …

Poor embryo development in mouse oocytes aged in vitro is associated with impaired calcium homeostasis

T Takahashi, H Igarashi, J Kawagoe… - Biology of …, 2009 - academic.oup.com
We examined whether impairment of intracellular Ca2+ homeostasis is related to poor
embryo development in in vitro-aged oocytes. We found that in vitro aging of mouse oocytes …

[HTML][HTML] Correlation of cumulus gene expression of GJA1, PRSS35, PTX3, and SERPINE2 with oocyte maturation, fertilization, and embryo development

SH Li, MH Lin, YM Hwu, CH Lu, LY Yeh… - Reproductive Biology …, 2015 - Springer
Background GJA1 and PTX3 were proposed as gene markers for oocyte and embryo
developmental competence, while SERPINE2 was reported to be associated with …

[HTML][HTML] Conserved miR-26b enhances ovarian granulosa cell apoptosis through HAS2-HA-CD44-Caspase-3 pathway by targeting HAS2

J Liu, F Tu, W Yao, X Li, Z Xie, H Liu, Q Li, Z Pan - Scientific reports, 2016 - nature.com
Abstract The hyaluronan synthase 2 (HAS2)-hyaluronic acid (HA)-CD44-Caspase-3
pathway is involved in ovarian granulosa cell (GC) functions in mammals. HAS2 is a key …

Quercetin supplemented diet improves follicular development, oocyte quality, and reduces ovarian apoptosis in rabbits during summer heat stress

Z Naseer, E Ahmad, ET Epikmen, U Uçan… - Theriogenology, 2017 - Elsevier
The present study was designed to test the modulatory effect of dietary quercetin on follicle
population, apoptosis, in vitro maturation rate and quality of oocytes in heat stressed female …

[HTML][HTML] HAS2-AS1 is a novel LH/hCG target gene regulating HAS2 expression and enhancing cumulus cells migration

Y Yung, L Ophir, GM Yerushalmi, M Baum… - Journal of ovarian …, 2019 - Springer
Background The cumulus expansion process is one of the LH mediated ovulatory
processes. Hyaluronan synthase 2 (HAS2) regulates the synthesis of hyaluronic acid, the …