EMT‐associated microRNAs and their roles in cancer stemness and drug resistance

G Pan, Y Liu, L Shang, F Zhou… - Cancer …, 2021 - Wiley Online Library
Epithelial‐to‐mesenchymal transition (EMT) is implicated in a wide array of malignant
behaviors of cancers, including proliferation, invasion, and metastasis. Most notably, previou …

Mechanisms of the Epithelial–Mesenchymal Transition and Tumor Microenvironment in Helicobacter pylori-Induced Gastric Cancer

J Baj, I Korona-Głowniak, A Forma, A Maani, E Sitarz… - Cells, 2020 - mdpi.com
Helicobacter pylori (H. pylori) is one of the most common human pathogens, affecting half of
the world's population. Approximately 20% of the infected patients develop gastric ulcers or …

Nanotechnology-empowered lung cancer therapy: from EMT role in cancer metastasis to application of nanoengineered structures for modulating growth and …

HM Saleem, P Ramaiah, J Gupta, AT Jalil… - Environmental …, 2023 - Elsevier
Lung cancer is one of the leading causes of death in both males and females, and it is the
first causes of cancer-related deaths. Chemotherapy, surgery and radiotherapy are …

SMAP: Similarity-based matrix factorization framework for inferring miRNA-disease association

J Ha - Knowledge-Based Systems, 2023 - Elsevier
Background: Based on increasing evidence, microRNAs (miRNAs) play significant roles in
various complex human diseases. Therefore, identifying the disease-related miRNAs could …

miR-410 induces both epithelial–mesenchymal transition and radioresistance through activation of the PI3K/mTOR pathway in non-small cell lung cancer

Y Yuan, H Liao, Q Pu, X Ke, X Hu, Y Ma… - Signal transduction and …, 2020 - nature.com
Radiotherapy remains one of the major treatments for non-small cell lung cancer (NSCLC)
patients; whereas intrinsic or acquired radioresistance limits its efficacy. Nevertheless, most …

NCMD: Node2vec-based neural collaborative filtering for predicting miRNA-disease association

J Ha, S Park - IEEE/ACM Transactions on Computational …, 2022 - ieeexplore.ieee.org
Numerous studies have reported that micro RNAs (miRNAs) play pivotal roles in disease
pathogenesis based on the deregulation of the expressions of target messenger RNAs …

MicroRNAs: Emerging oncogenic and tumor-suppressive regulators, biomarkers and therapeutic targets in lung cancer

S Tang, S Li, T Liu, Y He, H Hu, Y Zhu, S Tang, H Zhou - Cancer Letters, 2021 - Elsevier
Lung cancer is one of the most common solid tumors worldwide and the leading cause of
cancer-related deaths, causing a devastating impact on human health. The clinical …

A novel bioengineered miR-127 prodrug suppresses the growth and metastatic potential of triple-negative breast cancer cells

M Umeh-Garcia, C Simion, PY Ho, N Batra, AL Berg… - Cancer research, 2020 - AACR
Abstract miR-127 is downregulated in breast cancer, where it has been shown to suppress
the proliferation, migration, and invasion of breast cancer cells. In triple-negative breast …

Role of miRNA in lung cancer-potential biomarkers and therapies

X Du, J Zhang, J Wang, X Lin… - Current pharmaceutical …, 2017 - ingentaconnect.com
MicroRNAs (miRNAs) are small noncoding RNAs, which downregulate gene expression by
repressing or degrading mRNA targets. Lung cancer (LC), together with liver and colorectal …

miR‐25 promotes cell proliferation, migration, and invasion of non‐small‐cell lung cancer by targeting the LATS2/YAP signaling pathway

T Wu, H Hu, T Zhang, L Jiang, X Li, S Liu… - Oxidative medicine …, 2019 - Wiley Online Library
Metastasis is the leading cause of high mortality in lung cancer patients, and metastatic lung
cancer is difficult to treat. miRNAs are involved in various biological processes of cancer …