Recent developments in bioprocessing of recombinant proteins: expression hosts and process development
NK Tripathi, A Shrivastava - Frontiers in Bioengineering and …, 2019 - frontiersin.org
Infectious diseases, along with cancers, are among the main causes of death among
humans worldwide. The production of therapeutic proteins for treating diseases at large …
humans worldwide. The production of therapeutic proteins for treating diseases at large …
[HTML][HTML] Metabolic engineering of Pichia pastoris
Besides its use for efficient production of recombinant proteins the methylotrophic yeast
Pichia pastoris (syn. Komagataella spp.) has been increasingly employed as a platform to …
Pichia pastoris (syn. Komagataella spp.) has been increasingly employed as a platform to …
Methanol biotransformation toward high-level production of fatty acid derivatives by engineering the industrial yeast Pichia pastoris
P Cai, X Wu, J Deng, L Gao, Y Shen… - Proceedings of the …, 2022 - National Acad Sciences
Methanol-based biorefinery is a promising strategy to achieve carbon neutrality goals by
linking CO2 capture and solar energy storage. As a typical methylotroph, Pichia pastoris …
linking CO2 capture and solar energy storage. As a typical methylotroph, Pichia pastoris …
Advances in the synthesis of three typical tetraterpenoids including β-carotene, lycopene and astaxanthin
Y Jing, Y Wang, D Zhou, J Wang, J Li, J Sun… - Biotechnology …, 2022 - Elsevier
Carotenoids are natural pigments that widely exist in nature. Due to their excellent
antioxidant, anticancer and anti-inflammatory properties, carotenoids are commonly used in …
antioxidant, anticancer and anti-inflammatory properties, carotenoids are commonly used in …
[HTML][HTML] Development of synthetic biology tools to engineer Pichia pastoris as a chassis for the production of natural products
J Gao, L Jiang, J Lian - Synthetic and systems biotechnology, 2021 - Elsevier
The methylotrophic yeast Pichia pastoris (aka Komagataella phaffii) is one of the most
commonly used hosts for industrial production of recombinant proteins. As a non …
commonly used hosts for industrial production of recombinant proteins. As a non …
Standardization of Synthetic Biology Tools and Assembly Methods for Saccharomyces cerevisiae and Emerging Yeast Species
As redesigning organisms using engineering principles is one of the purposes of synthetic
biology (SynBio), the standardization of experimental methods and DNA parts is becoming …
biology (SynBio), the standardization of experimental methods and DNA parts is becoming …
Synthetic Biology Toolkit for Marker-Less Integration of Multigene Pathways into Pichia pastoris via CRISPR/Cas9
J Gao, J Xu, Y Zuo, C Ye, L Jiang, L Feng… - ACS Synthetic …, 2022 - ACS Publications
Pichia pastoris, an important methylotrophic yeast, is currently mainly used for the
expression of recombinant proteins and has great potential applications in the production of …
expression of recombinant proteins and has great potential applications in the production of …
Economical production of Pichia pastoris single cell protein from methanol at industrial pilot scale
J Meng, S Liu, L Gao, K Hong, S Liu, X Wu - Microbial Cell Factories, 2023 - Springer
Background Methanol, synthesized from CO2, is a potentially sustainable one-carbon (C1)
resource for biomanufacturing. The use of methanol as a feedstock to produce single cell …
resource for biomanufacturing. The use of methanol as a feedstock to produce single cell …
CRISPR–Cas9-mediated genomic multiloci integration in Pichia pastoris
Q Liu, X Shi, L Song, H Liu, X Zhou, Q Wang… - Microbial cell …, 2019 - Springer
Abstract Background Pichia pastoris (syn. Komagataella phaffii) is a widely used generally
recognized as safe host for heterologous expression of proteins in both industry and …
recognized as safe host for heterologous expression of proteins in both industry and …
Current advances of Pichia pastoris as cell factories for production of recombinant proteins
Pichia pastoris (syn. Komagataella spp.) has attracted extensive attention as an efficient
platform for recombinant protein (RP) production. For obtaining a higher protein titer, many …
platform for recombinant protein (RP) production. For obtaining a higher protein titer, many …