Regulatory network of miRNA on its target: coordination between transcriptional and post-transcriptional regulation of gene expression
MicroRNAs (miRNAs) are a class of endogenous small noncoding RNAs that participate in a
majority of biological processes via regulating target gene expression. The post …
majority of biological processes via regulating target gene expression. The post …
Nuclear functions of mammalian MicroRNAs in gene regulation, immunity and cancer
H Liu, C Lei, Q He, Z Pan, D Xiao, Y Tao - Molecular cancer, 2018 - Springer
MicroRNAs (miRNAs) are endogenous non-coding RNAs that contain approximately 22
nucleotides. They serve as key regulators in various biological processes and their …
nucleotides. They serve as key regulators in various biological processes and their …
Circ HIPK 3 sponges miR‐558 to suppress heparanase expression in bladder cancer cells
Y Li, F Zheng, X Xiao, F Xie, D Tao, C Huang, D Liu… - EMBO …, 2017 - embopress.org
Increasing evidences suggest that circular RNA s (circ RNA s) exert crucial functions in
regulating gene expression. In this study, we perform RNA‐seq and identify 6,154 distinct …
regulating gene expression. In this study, we perform RNA‐seq and identify 6,154 distinct …
Neuroinflammation and depression: microglia activation, extracellular microvesicles and microRNA dysregulation
D Brites, A Fernandes - Frontiers in cellular neuroscience, 2015 - frontiersin.org
Patients with chronic inflammation are often associated with the emergence of depression
symptoms, while diagnosed depressed patients show increased levels of circulating …
symptoms, while diagnosed depressed patients show increased levels of circulating …
Progress in microRNA delivery
Y Zhang, Z Wang, RA Gemeinhart - Journal of controlled release, 2013 - Elsevier
MicroRNAs (miRNAs) are non-coding endogenous RNAs that direct post-transcriptional
regulation of gene expression by several mechanisms. Activity is primarily through binding …
regulation of gene expression by several mechanisms. Activity is primarily through binding …
The miRNA–target interactions: An underestimated intricacy
MicroRNAs (miRNAs) play indispensable roles in posttranscriptional gene regulation. Their
cellular regulatory impact is determined not solely by their sheer number, which likely …
cellular regulatory impact is determined not solely by their sheer number, which likely …
The complexity of the translation ability of circRNAs
JT Granados-Riveron, G Aquino-Jarquin - Biochimica et Biophysica Acta …, 2016 - Elsevier
Circular RNAs (circRNAs) are a new class of long non-coding RNAs that play a potential
role in gene expression regulation, acting as efficient microRNAs sponges. The latest …
role in gene expression regulation, acting as efficient microRNAs sponges. The latest …
Epigenetics and microRNAs in cancer
A Ramassone, S Pagotto, A Veronese… - International journal of …, 2018 - mdpi.com
The ability to reprogram the transcriptional circuitry by remodeling the three-dimensional
structure of the genome is exploited by cancer cells to promote tumorigenesis. This …
structure of the genome is exploited by cancer cells to promote tumorigenesis. This …
Upregulation of Cyclin B1 by miRNA and its implications in cancer
V Huang, RF Place, V Portnoy, J Wang, Z Qi… - Nucleic acids …, 2012 - academic.oup.com
It is largely recognized that microRNAs (miRNAs) function to silence gene expression by
targeting 3′ UTR regions. However, miRNAs have also been implicated to positively …
targeting 3′ UTR regions. However, miRNAs have also been implicated to positively …
Mitochondrial miRNA determines chemoresistance by reprogramming metabolism and regulating mitochondrial transcription
Abstract miRNAs that translocate from the nucleus to mitochondria are referred to as
mitochondrial microRNAs (mitomiR). mitomiRs have been shown to modulate the …
mitochondrial microRNAs (mitomiR). mitomiRs have been shown to modulate the …