Homocysteine (Hcy) metabolism is crucial for regulating methionine availability, protein
homeostasis, and DNA-methylation presenting, therefore, key pathways in post-genomic …

Folate (vitamin B9) is found in some water-soluble foods or as a synthetic form of folic acid
and is involved in many essential biochemical processes. Dietary folate is converted into …

Pyoderma gangrenosum (PG), hidradenitis suppurativa (HS), and the associated
autoinflammatory syndromes, including pyogenic arthritis, pyoderma gangrenosum, and …

Background Despite conflicting results, considerable evidence suggests the association
between single nucleotide polymorphisms in MTHFR, XRCC1 and OGG1 genes and, risk of …

Lynch syndrome (LS) is characterised by an increased risk of developing colorectal cancer
(CRC) and other extracolonic epithelial cancers. It is caused by pathogenic germline …

Common variants of genes involved in DNA damage correction [tumor protein p53 (TP53),
murine double 2 homolog oncoprotein (MDM2) and ataxia‑telengiectasia mutated (ATM)] …

Background The detection and analysis of methylene tetrahydrofolate reductase (MTHFR)
C677T single nucleotide polymorphism (SNP) from blood samples is time-consuming and …

Methylenetetrahydrofolate reductase (MTHFR), a folate-dependent enzyme, is reportedly
involved in several cancer types. The MTHFR C677T polymorphism influences many …

Results: The present data showed a strong significant association between the CT and TT of
MTHFR (C677T), and AC and CC of (A1289C) with the susceptibility of BC showing highly …

Background Methylenetetrahydrofolate reductase (MTHFR) small nucleotide polymorphisms
(SNPs) have been suggested as risk, prognostic, and predictive factors for colorectal cancer …