Inflammatory Response and Post-Cardiac Arrest Syndrome: Insights from the STEROHCA trial and Implications for the Future of Resuscitation

JB Lascarrou, G Geri - Resuscitation, 2024 - resuscitationjournal.com
Post-cardiac arrest syndrome (PCAS) is a major determinant of early mortality after cardiac
arrest. To date, interventions aimed at this potential therapeutic target have failed to …

Insight into the mechanisms of therapeutic hypothermia for asphyxia cardiac arrest using a comprehensive approach of GC-MS/MS and UPLC-Q-TOF-MS/MS based …

Y Zhang, Y Feng, F Chen, J Yu, X Liu, Y Liu, J Ouyang… - Heliyon, 2023 - cell.com
Cardiac arrest (CA) is a severe worldwide health problem. Therapeutic hypothermia is
widely used to reduce the cardiac injury and improve the neurological outcomes after CA …

[HTML][HTML] Differential Roles of Interleukin-6 in Severe Acute Respiratory Syndrome-Coronavirus-2 Infection and Cardiometabolic Diseases

J Ren, XQ Wang, T Nakao, P Libby… - Cardiology Discovery, 2023 - journals.lww.com
Severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) infection can lead to a
cytokine storm, unleashed in part by pyroptosis of virus-infected macrophages and …

УЧАСТИЕ ИММУНОВОСПАЛИТЕЛЬНЫХ ПРОЦЕССОВ В ПАТОГЕНЕЗЕ АТЕРОСКЛЕРОЗА

ВФ Мордовин, ИВ Зюбанова, МА Манукян… - Комплексные …, 2023 - nii-kpssz.com
Резюме Хроническое низкоинтенсивное воспаление в настоящее время
рассматривается как один из наиболее значимых факторов риска развития сердечно …

1, 25 (OH) 2 D 3 prevents the occurrence of high altitude sickness by regulating the body's immune homeostasis

Y Wang, X Lin, C Dai, M Liu, H Su, Q Cheng, F Zhao… - 2024 - researchsquare.com
This study mainly investigated the clinical efficacy and related mechanisms of 1, 25 (OH)
2D3 in preventing high altitude sickness through human trials and animal experiments …

Exploring the Factors that Influence Pivoting in Student Startups: A Case Study of Entrepreneurship Student of SBM ITB Analysis

E Ariella - Jurnal Syntax Transformation, 2023 - jurnal.syntaxtransformation.co.id
According to recent news sources and journals, the growth of start-ups in today's world is on
the rise. The pandemic has played a significant role in this growth, with many people starting …

Novel Drug Targets for Atrial Fibrillation Identified Through Mendelian Randomization Analysis

Z Ning, Y Huang, H Lu, Y Zhou, T Tu, F Ouyang, Y Liu… - 2023 - researchsquare.com
Purpose: Novel, effective, and safe preventive therapy targets for AF are still warranted.
Circulating proteins with causal genetic evidence represents promising candidates. We …

Black swans or red herrings–Inflammatory derangement after cardiac arrest

KF Kernan, PM Kochanek - Resuscitation, 2022 - resuscitationjournal.com
Could the post-inflammatory state that follows cardiac arrest be a mechanistic black swan?
In this issue of Resuscitation, Langeland and colleagues help us understand the potential …

Single-cell transcriptomics reveal hyperacute cytokine and immune checkpoint axis in patients with poor neurological outcomes after cardiac arrest

T Tamura, C Cheng, W Chen, LT Merriam… - bioRxiv, 2022 - biorxiv.org
Neurological injury is a major driver of mortality among patients hospitalized after cardiac
arrest (CA). The early systemic inflammatory response after CA is associated with …

Hemoadsorption after cardiac arrest–not quite the “shelter from the cytokine storm” we were hoping for

T Drabek - Resuscitation, 2022 - resuscitationjournal.com
Resuscitation pioneers Negovsky and Safar blamed body-percolating “evil spirits” for
perpetuating the “post-resuscitation disease”, 1 ie the complex pathophysiologic …