Perineuronal nets (PNNs) are extracellular matrix (ECM) chondroitin sulfate proteoglycan
(CSPG)-containing structures that surround the soma and dendrites of various mammalian …

Perineuronal nets (PNNs) are unique extracellular matrix structures that wrap around certain
neurons in the CNS during development and control plasticity in the adult CNS. They appear …

During nervous system development, an extracellular matrix (ECM) plays a pivotal role
through surface topography and microenvironment signals in neurons and neurites …

The relationship between neurons and perineuronal nets (PNNs) is attracting attention as a
central mechanism controlling brain plasticity. In the cortex, PNNs primarily surround …

In the adult brain, the extracellular matrix (ECM) influences recovery after injury,
susceptibility to mental disorders, and is in general a strong regulator of neuronal plasticity …

Perineuronal nets (PNNs) are chondroitin sulphate proteoglycan-containing structures on
the neuronal surface that have been implicated in the control of neuroplasticity and memory …

Just as the epigenome, the proteome and the electrophysiological properties of a cell
influence its function, so too do its intrinsic mechanical properties and its extrinsic …

In the last decade, tremendous progress has been made in understanding the biology of
microglia–ie the fascinating immigrated resident immune cell population of the central …

Inherent limitations of the traditional approaches to study brain function and disease, such
as rodent models and 2D cell culture platforms, have led to the development of 3D in vitro …

Intracortical microelectrodes are a critical component of brain-machine interface (BMI)
systems. The recording performance of intracortical microelectrodes used for both basic …