Perineuronal nets (PNNs) are aggregations of extracellular matrix molecules that are critical
for plasticity. Their altered development or changes during adulthood appear to contribute to …

Although the molecular mechanisms underlying methylmercury toxicity are not entirely
understood, the observed neurotoxicity in early-life is attributed to the covalent binding of …

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by
progressive upper and lower motor neuron (MN) degeneration with unclear pathology. The …

Background Alcohol exposure leads to changes in the extracellular matrix (ECM) in the
brain, which profoundly impacts neuronal plasticity. Perineuronal nets (PN s) are specialized …

Ankyrin scaffolding proteins are critical for membrane domain organization and protein
stabilization in many different cell types including neurons. In the cerebellum, Ankyrin-R …

As part of the extracellular matrix (ECM), perineuronal nets (PNs) are polyanionic,
chondroitin sulfate proteoglycan (CSPG)-rich coatings of certain neurons, known to be …

Chondroitin sulfate proteoglycans (CSPGs) are the main active component of perineuronal
nets (PNNs). Digestion of the glycosaminoglycan chains of CSPGs with chondroitinase ABC …

The aim of the present study was to examine the roles of l-fucose and the
glycosaminoglycans (GAGs) keratan sulfate (KS) and chondroitin sulfate/dermatan sulfate …

The homeoprotein family comprises~ 300 transcription factors and was long seen as
primarily involved in developmental programs through cell autonomous regulation …

The central nervous system/peripheral nervous system (CNS/PNS) extracellular matrix is a
dynamic and highly interactive space‐filling, cell‐supportive, matrix‐stabilising, hydrating …