[HTML][HTML] Targeting the chromatin structural changes of antitumor immunity

N Li, D Lun, N Gong, G Meng, X Du, H Wang… - Journal of …, 2023 - Elsevier
Epigenomic imbalance drives abnormal transcriptional processes, promoting the onset and
progression of cancer. Although defective gene regulation generally affects carcinogenesis …

New histone lysine acylation biomarkers and their roles in epigenetic regulation

Q Fu, A Cat, YG Zheng - Current Protocols, 2023 - Wiley Online Library
Protein posttranslational modification (PTM) is a biochemical mechanism benefitting cellular
adaptation to dynamic intracellular and environmental conditions. Recently, several …

Promiscuous Enzymes for Residue‐Specific Peptide and Protein Late‐Stage Functionalization

AK Alexander, SI Elshahawi - ChemBioChem, 2023 - Wiley Online Library
The late‐stage functionalization of peptides and proteins holds significant promise for drug
discovery and facilitates bioorthogonal chemistry. This selective functionalization leads to …