Motile ciliopathies

J Wallmeier, KG Nielsen, CE Kuehni… - Nature reviews Disease …, 2020 - nature.com
Motile cilia are highly complex hair-like organelles of epithelial cells lining the surface of
various organ systems. Genetic mutations (usually with autosomal recessive inheritance) …

Motile cilia and airway disease

M Legendre, LE Zaragosi, HM Mitchison - Seminars in cell & …, 2021 - Elsevier
A finely regulated system of airway epithelial development governs the differentiation of
motile ciliated cells of the human respiratory tract, conferring the body's mucociliary …

Understanding pathways to death in patients with COVID-19

JL Vincent, FS Taccone - The Lancet Respiratory Medicine, 2020 - thelancet.com
Since the first cases of coronavirus disease 2019 (COVID-19), caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), were identified in China in December …

The impact of primary ciliary dyskinesia on female and male fertility: a narrative review

L Newman, J Chopra, C Dossett… - Human …, 2023 - academic.oup.com
BACKGROUND Primary ciliary dyskinesia (PCD) is a genetic condition affecting the
structure and function of sperm flagellum and motile cilia including those in the male and …

International consensus guideline for reporting transmission electron microscopy results in the diagnosis of primary ciliary dyskinesia (BEAT PCD TEM Criteria)

A Shoemark, M Boon, C Brochhausen… - European …, 2020 - Eur Respiratory Soc
Primary ciliary dyskinesia (PCD) is a heterogeneous genetic condition. European and North
American diagnostic guidelines recommend transmission electron microscopy (TEM) as one …

Diagnosis of primary ciliary dyskinesia

M Goutaki, A Shoemark - Clinics in chest medicine, 2022 - chestmed.theclinics.com
Primary ciliary dyskinesia (PCD) is a rare multiorgan disease caused by genetic mutations
resulting in defects in motile cilia. Because cilia are responsible for clearing the secretions …

Progress in diagnosing primary ciliary dyskinesia: the North American perspective

MG O'Connor, A Horani, AJ Shapiro - Diagnostics, 2021 - mdpi.com
Primary Ciliary Dyskinesia (PCD) is a rare, under-recognized disease that affects respiratory
ciliary function, resulting in chronic oto-sino-pulmonary disease. The PCD clinical phenotype …

Primary ciliary dyskinesia

J Raidt, NT Loges, H Olbrich, J Wallmeier… - La Presse Médicale, 2023 - Elsevier
Background and objectives Primary ciliary dyskinesia (PCD, ORPHA: 244) is a group of rare
genetic disorders characterized by dysfunction of motile cilia. It is phenotypically and …

Primary ciliary dyskinesia

A Shoemark, K Harman - Seminars in respiratory and critical …, 2021 - thieme-connect.com
Primary ciliary dyskinesia (PCD) is an inherited cause of bronchiectasis. The estimated PCD
prevalence in children with bronchiectasis is up to 26% and in adults with bronchiectasis is 1 …

Primary Ciliary Dyskinesia

WB Wee, BA Kinghorn, SD Davis, TW Ferkol… - …, 2024 - publications.aap.org
Primary ciliary dyskinesia (PCD) is a rare, genetic disease characterized by dysfunctional
motile cilia and abnormal mucociliary clearance, resulting in chronic sino-oto-pulmonary …