[HTML][HTML] Critical roles of circular RNA in tumor metastasis via acting as a sponge of miRNA/isomiR

L Guo, L Jia, L Luo, X Xu, Y Xiang, Y Ren… - International Journal of …, 2022 - mdpi.com
Circular RNAs (circRNAs), a class of new endogenous non-coding RNAs (ncRNAs), are
closely related to the carcinogenic process and play a critical role in tumor metastasis …

Up-regulated circular RNAs in colorectal cancer: New entities for therapy and tools for identification of therapeutic targets

UH Weidle, A Nopora - Cancer Genomics & Proteomics, 2023 - cgp.iiarjournals.org
Patients with disseminated colorectal cancer have a dismal prognosis with a 5-year survival
rate of only 13%. In order to identify new treatment modalities and new targets, we searched …

Circ_ARHGAP32 acts as miR-665 sponge to upregulate FGF2 to promote ox-LDL induced vascular smooth muscle cells proliferation and migration

Y Wang, W Pei, P Lu - Clinical Hemorheology and …, 2022 - content.iospress.com
BACKGROUND: Circular RNA (circRNA) is considered to be an important regulator of
human diseases, including atherosclerosis (AS). However, the role of circ_ARHGAP32 in AS …

Deregulated circRNAs in Epithelial Ovarian Cancer With Activity in Preclinical In Vivo Models: Identification of Targets and New Modalities for Therapeutic Intervention

UH Weidle, F Birzele - Cancer Genomics & Proteomics, 2024 - cgp.iiarjournals.org
Epithelial ovarian cancer (EOC) is associated with a dismal prognosis due to development
of resistance to chemotherapy and metastasis in the peritoneal cavity and distant organs. In …

Hepatocellular Carcinoma: Up-regulated Circular RNAs Which Mediate Efficacy in Preclinical In Vivo Models

UH Weidle, A Nopora - Cancer Genomics & Proteomics, 2023 - cgp.iiarjournals.org
Hepatocellular carcinoma (HCC) ranges as number two with respect to the incidence of
tumors and is associated with a dismal prognosis. The therapeutic efficacy of approved multi …

血清circDUSP16 预测可切除胃癌辅助化疗疗效和预后的临床观察

时阳, 张路遥, 曹婷婷, 张建广, 金国花 - 临床肿瘤学杂志, 2023 - manu65.magtech.com.cn
目的探讨血清circDUSP16 是否可作为预测可切除胃癌(GC) 辅助化疗疗效和预后的潜在生物学
标志物. 方法收集2017 年1 月至2021 年5 月期间在我院接受根治性胃癌切除术的226 例GC …