Blockers of the renin–angiotensin–aldosterone system (RAAS), that is, renin inhibitors,
angiotensin (Ang)-converting enzyme (ACE) inhibitors, Ang II type 1 receptor antagonists …

Angiotensin receptor antagonists: focus on losartan. | AHRO : Austin Health Research
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Background Obstructive sleep apnea (OSA) is the most common cause of resistant
hypertension, which has been proposed to result from activation of the renin–angiotensin …

Small interfering RNAs (siRNAs) targeting hepatic angiotensinogen (Agt) may provide long-
lasting antihypertensive effects, but the optimal approach remains unclear. Here, we …

Objective: To undertake a systematic review of the studies on the effect of antihypertensive
treatment on ambulatory (ABP) and office blood pressure in order to obtain a differential …

Excess production of superoxide anion in response to angiotensin II plays a central role in
the transduction of signal molecules and the regulation of vascular tone. We examined the …

The primary objectives of this double-blind study were to compare the antihypertensive
efficacy and tolerability of irbesartan and losartan, two angiotensin II (AT1 subtype) receptor …

Objective Angiotensin II induces myocardial hypertrophy. We hypothesized that blockade of
angiotensin II subtype 1 (AT 1) receptors by the AT 1-receptor antagonist irbesartan would …

Objective 30 mm Hg drops in office systolic blood pressure are reported in trials of renal
denervation, but ambulatory reductions are much smaller. This disparity is assumed to have …

Background—Anemia is common in patients with chronic heart failure (CHF) and is
associated with a poor prognosis. However, only a minority of patients with CHF have …