Neural tube defects (NTDs) are the second most common congenital malformations in
humans affecting the development of the central nervous system. Although NTD …

Neural tube defects (NTDs), including spina bifida and anencephaly, are severe birth
defects of the central nervous system that originate during embryonic development when the …

A clear, engaging writing style, hundreds of full-color images, and new information
throughout make Volpe's Neurology of the Newborn, 6th Edition, an indispensable resource …

With 4 mg folic acid daily, it may take 20 weeks to reach red-blood-cell folate levels between
1050 and 1340 nmol/L, optimal for reduction of the neural tube defect risk. Therefore, folic …

Although understanding how soluble cues direct cellular processes revolutionised the study
of cell biology in the second half of the 20th century, over the last two decades, new insights …

Evaluation of the central nervous system (CNS) in the developing mouse presents unique
challenges, given the complexity of ontogenesis, marked structural reorganization over very …

Nonsyndromic orofacial clefts (OFCs) are a heterogeneous group of common craniofacial
birth defects with complex etiologies that include genetic and environmental risk factors …

Correct notochord and neural tube (NT) formation is crucial to the development of the central
nervous system and midline structures. Integrated biochemical and biophysical signaling …

Shape-Memory Polymers (SMPs) are considered a kind of smart material able to modify
size, shape, stiffness and strain in response to different external (heat, electric and magnetic …

Gastrulation and neurulation are successive morphogenetic processes that play key roles in
shaping the basic embryonic body plan. Importantly, they operate through common cellular …