Exosome processing and characterization approaches for research and technology development

JJ Lai, ZL Chau, SY Chen, JJ Hill… - Advanced …, 2022 - Wiley Online Library
Exosomes are extracellular vesicles that share components of their parent cells and are
attractive in biotechnology and biomedical research as potential disease biomarkers as well …

[HTML][HTML] Small extracellular vesicles isolation and separation: Current techniques, pending questions and clinical applications

Y Jia, L Yu, T Ma, W Xu, H Qian, Y Sun, H Shi - Theranostics, 2022 - ncbi.nlm.nih.gov
Extracellular vesicles, especially small extracellular vesicles (sEVs) are now accepted as
important messengers in cell-to-cell communication and as a promising drug delivery …

Minimal information for studies of extracellular vesicles (MISEV2023): From basic to advanced approaches

JA Welsh, DCI Goberdhan, L O'Driscoll… - Journal of …, 2024 - Wiley Online Library
Extracellular vesicles (EVs), through their complex cargo, can reflect the state of their cell of
origin and change the functions and phenotypes of other cells. These features indicate …

Molecular evaluation of five different isolation methods for extracellular vesicles reveals different clinical applicability and subcellular origin

RE Veerman, L Teeuwen, P Czarnewski… - Journal of …, 2021 - Wiley Online Library
Extracellular vesicles (EVs) are increasingly tested as therapeutic vehicles and biomarkers,
but still EV subtypes are not fully characterised. To isolate EVs with few co‐isolated entities …

[HTML][HTML] Plant exosome-like nanovesicles: emerging therapeutics and drug delivery nanoplatforms

HA Dad, TW Gu, AQ Zhu, LQ Huang, LH Peng - Molecular Therapy, 2021 - cell.com
Plant exosome-like nanovesicles, being innately replete with bioactive lipids, proteins, RNA,
and other pharmacologically active molecules, offer unique morphological and …

[HTML][HTML] Regulation of exosome production and cargo sorting

H Wei, Q Chen, L Lin, C Sha, T Li, Y Liu… - … journal of biological …, 2021 - ncbi.nlm.nih.gov
Cellular communication can be mediated by the exchange of biological information, mainly
in the form of proteins and RNAs. This can occur when extracellular vesicles, such as …

[HTML][HTML] Review of the isolation, characterization, biological function, and multifarious therapeutic approaches of exosomes

S Gurunathan, MH Kang, M Jeyaraj, M Qasim, JH Kim - Cells, 2019 - mdpi.com
Exosomes are extracellular vesicles that contain a specific composition of proteins, lipids,
RNA, and DNA. They are derived from endocytic membranes and can transfer signals to …

Using single-vesicle technologies to unravel the heterogeneity of extracellular vesicles

G Bordanaba-Florit, F Royo, SG Kruglik… - Nature …, 2021 - nature.com
Extracellular vesicles (EVs) are heterogeneous lipid containers with a complex molecular
cargo comprising several populations with unique roles in biological processes. These …

Isolation and characterization of extracellular vesicles and future directions in diagnosis and therapy

KP De Sousa, I Rossi, M Abdullahi… - Wiley …, 2023 - Wiley Online Library
Extracellular vesicles (EVs) are a unique and heterogeneous class of lipid bilayer
nanoparticles secreted by most cells. EVs are regarded as important mediators of …

Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the …

C Théry, KW Witwer, E Aikawa… - Journal of …, 2018 - Wiley Online Library
The last decade has seen a sharp increase in the number of scientific publications
describing physiological and pathological functions of extracellular vesicles (EVs), a …