[HTML][HTML] Testing drug release from medicated contact lenses: The missing link to predict in vivo performance

AF Pereira-da-Mota, CM Phan, A Concheiro… - Journal of Controlled …, 2022 - Elsevier
Contact lenses (CLs) offer a wide variety of advantages as ocular drug-releasing platforms,
but the feasibility of medicated CL development is constrained by numerous scientific …

Topical drug delivery devices: A review

CJF Bertens, M Gijs, FJHM van den Biggelaar… - Experimental eye …, 2018 - Elsevier
For the treatment and prevention of ocular diseases, most patients are treated with
conventional drug delivery formulations such as eye drops or ointments. However, eye …

Ocular drug delivery system: a reference to natural polymers

P Pahuja, S Arora, P Pawar - Expert Opinion on Drug Delivery, 2012 - Taylor & Francis
Introduction: Ocular drug delivery is a very challenging endeavor due to the unique
anatomical and physiological barriers. The low ocular bioavailability (< 10%) obtained from …

A review of implantable intravitreal drug delivery technologies for the treatment of posterior segment eye diseases

YE Choonara, V Pillay, MP Danckwerts… - Journal of …, 2010 - Elsevier
Intravitreal implantable device technology utilizes engineered materials or devices that
could revolutionize the treatment of posterior segment eye diseases by affording localized …

Delivery devices for the administration of paediatric formulations: overview of current practice, challenges and recent developments

J Walsh, D Bickmann, J Breitkreutz… - International journal of …, 2011 - Elsevier
Abstract The European Paediatric Formulation Initiative (EuPFI), a group consisting of
paediatric formulation experts from industry, academia and clinical pharmacy was founded …

Nanocrystal for ocular drug delivery: hope or hype

OP Sharma, V Patel, T Mehta - Drug delivery and translational research, 2016 - Springer
The complexity of the structure and nature of the eye emanates a challenge for drug delivery
to formulation scientists. Lower bioavailability concern of conventional ocular formulation …

Hydrophilic surface coatings with embedded biocidal silver nanoparticles and sodium heparin for central venous catheters

KNJ Stevens, S Croes, RS Boersma, EE Stobberingh… - Biomaterials, 2011 - Elsevier
Central venous catheters (CVCs) have become indispensable in the treatment of neonates
and patients undergoing chemotherapy or hemodialysis. A CVC provides easy access to the …

Advances in ocular drug delivery

M Rawas-Qalaji, CA Williams - Current eye research, 2012 - Taylor & Francis
Eye drops have long been the primary ocular drug delivery dosage form used to treat ocular
disorders ranging from superficial conditions to intravitreal diseases. The ocular anatomical …

Challenges and solutions in topical ocular drug-delivery systems

M Ali, ME Byrne - Expert review of clinical pharmacology, 2008 - Taylor & Francis
Vision significantly affects quality of life and the treatment of ocular disease poses a number
of unique challenges. This review presents the major challenges faced during topical ocular …

Ocular delivery systems for topical application of anti-infective agents

L Duxfield, R Sultana, R Wang… - Drug Development …, 2016 - Taylor & Francis
For the treatment of anterior eye segment infections using anti-infective agents, topical
ocular application is the most convenient route of administration. However, topical delivery …