Treatment trials in young patients with chronic obstructive pulmonary disease and pre–chronic obstructive pulmonary disease patients: time to move forward
Chronic obstructive pulmonary disease (COPD) is the end result of a series of dynamic and
cumulative gene–environment interactions over a lifetime. The evolving understanding of …
cumulative gene–environment interactions over a lifetime. The evolving understanding of …
Imaging advances in chronic obstructive pulmonary disease. Insights from the genetic epidemiology of chronic obstructive pulmonary disease (COPDGene) study
SP Bhatt, GR Washko, EA Hoffman… - American journal of …, 2019 - atsjournals.org
The Genetic Epidemiology of Chronic Obstructive Pulmonary Disease (COPDGene) study,
which began in 2007, is an ongoing multicenter observational cohort study of more than …
which began in 2007, is an ongoing multicenter observational cohort study of more than …
[HTML][HTML] X-ray dark-field chest imaging for detection and quantification of emphysema in patients with chronic obstructive pulmonary disease: a diagnostic accuracy …
Background Although advanced medical imaging technologies give detailed diagnostic
information, a low-dose, fast, and inexpensive option for early detection of respiratory …
information, a low-dose, fast, and inexpensive option for early detection of respiratory …
Mucus plugs and emphysema in the pathophysiology of airflow obstruction and hypoxemia in smokers
EM Dunican, BM Elicker, T Henry… - American journal of …, 2021 - atsjournals.org
Rationale: The relative roles of mucus plugs and emphysema in mechanisms of airflow
limitation and hypoxemia in smokers with chronic obstructive pulmonary disease (COPD) …
limitation and hypoxemia in smokers with chronic obstructive pulmonary disease (COPD) …
Deep learning enables automatic classification of emphysema pattern at CT
SM Humphries, AM Notary, JP Centeno, MJ Strand… - Radiology, 2020 - pubs.rsna.org
Background Pattern of emphysema at chest CT, scored visually by using the Fleischner
Society system, is associated with physiologic impairment and mortality risk. Purpose To …
Society system, is associated with physiologic impairment and mortality risk. Purpose To …
[HTML][HTML] Chronic obstructive pulmonary disease and related phenotypes: polygenic risk scores in population-based and case-control cohorts
Background Genetic factors influence chronic obstructive pulmonary disease (COPD) risk,
but the individual variants that have been identified have small effects. We hypothesised that …
but the individual variants that have been identified have small effects. We hypothesised that …
[HTML][HTML] Validated imaging biomarkers as decision-making tools in clinical trials and routine practice: current status and recommendations from the EIBALL …
NM deSouza, E Achten, A Alberich-Bayarri… - Insights into …, 2019 - Springer
Observer-driven pattern recognition is the standard for interpretation of medical images. To
achieve global parity in interpretation, semi-quantitative scoring systems have been …
achieve global parity in interpretation, semi-quantitative scoring systems have been …
[HTML][HTML] Survival in COPD patients treated with bronchoscopic lung volume reduction
Background and objective Severe COPD patients can significantly benefit from
bronchoscopic lung volume reduction (BLVR) treatments with coils or endobronchial valves …
bronchoscopic lung volume reduction (BLVR) treatments with coils or endobronchial valves …
Qualitative and quantitative assessment of emphysema using dark-field chest radiography
Background Dark-field chest radiography allows for assessment of lung alveolar structure by
exploiting wave optical properties of x-rays. Purpose To evaluate the qualitative and …
exploiting wave optical properties of x-rays. Purpose To evaluate the qualitative and …
Automated CT staging of chronic obstructive pulmonary disease severity for predicting disease progression and mortality with a deep learning convolutional neural …
KA Hasenstab, N Yuan, T Retson… - Radiology …, 2021 - pubs.rsna.org
Purpose To develop a deep learning–based algorithm to stage the severity of chronic
obstructive pulmonary disease (COPD) through quantification of emphysema and air …
obstructive pulmonary disease (COPD) through quantification of emphysema and air …