Antiplatelet use in ischemic stroke

M Kamarova, S Baig, H Patel, K Monks… - Annals of …, 2022 - journals.sagepub.com
Objective: A literature review of antiplatelet agents for primary and secondary stroke
prevention, including mechanism of action, cost, and reasons for lack of benefit. Data …

[HTML][HTML] CYP2B6 functional variability in drug metabolism and exposure across populations—implication for drug safety, dosing, and individualized therapy

IM Langmia, KS Just, S Yamoune, J Brockmöller… - Frontiers in …, 2021 - frontiersin.org
Adverse drug reactions (ADRs) are one of the major causes of morbidity and mortality
worldwide. It is well-known that individual genetic make-up is one of the causative factors of …

Defined drug release from 3D-printed composite tablets consisting of drug-loaded polyvinylalcohol and a water-soluble or water-insoluble polymer filler

T Tagami, N Nagata, N Hayashi, E Ogawa… - International journal of …, 2018 - Elsevier
Abstract 3D-printed tablets are a promising new approach for personalized medicine. In this
study, we fabricated composite tablets consisting of two components, a drug and a filler, by …

[HTML][HTML] Pharmacogenomics and COVID-19: clinical implications of human genome interactions with repurposed drugs

OA Badary - The pharmacogenomics journal, 2021 - nature.com
The outbreak of Coronavirus disease 2019 (COVID-19) has evolved into an emergent global
pandemic. Many drugs without established efficacy are being used to treat COVID-19 …

Holmium laser enucleation of the prostate in patients requiring anticoagulation

M Rivera, A Krambeck, J Lingeman - Current urology reports, 2017 - Springer
Abstract Purpose of Review This is to evaluate and discuss the literature surrounding
holmium laser enucleation of the prostate (HoLEP) in patients on anticoagulation. Recent …

A review of cannabis and interactions with anticoagulant and antiplatelet agents

J Greger, V Bates, L Mechtler… - The Journal of Clinical …, 2020 - Wiley Online Library
Legalization of medical cannabis has occurred in 33 states and the District of Columbia, and
recreational use has increased exponentially since 2013. As a result, it is important to …

Interactions between clopidogrel and traditional Chinese medicine

Y Hu, J Wang - Journal of Thrombosis and Thrombolysis, 2019 - Springer
The use of traditional Chinese medicine (TCM) has obtained more and more acceptance all
over the world due to its multi-target and multi-level function characteristics. Clopidogrel is a …

[HTML][HTML] Influence of genetic polymorphisms in P2Y12 receptor signaling pathway on antiplatelet response to clopidogrel in coronary heart disease

YJ Zhang, DJ Li, ZY Li, XL Hu, H Li, QL Ma… - BMC cardiovascular …, 2022 - Springer
Backgrounds Remarkable interindividual variability in clopidogrel response is observed,
genetic polymorphisms in P2RY12 and its signal pathway is supposed to affect clopidogrel …

The mechanisms of nucleotide actions in insulin resistance

K Liu, X Jin, X Zhang, H Lian, J Ye - Journal of Genetics and Genomics, 2022 - Elsevier
Insulin resistance contributes to metabolic disorders in obesity and type 2 diabetes. In
mechanisms of insulin resistance, the roles of glucose, fatty acids, and amino acids have …

[HTML][HTML] Therapeutic drug monitoring and pharmacogenetic testing in northern China

C Zhang, J Lei, Y Liu, Y Wang, L Huang… - Frontiers in …, 2021 - frontiersin.org
Background: Therapeutic drug monitoring (TDM) and pharmacogenetic (PGx) testing are
widely used as approaches to improve individualized (personalized) pharmacotherapy …