Bronchiectasis refers to both a clinical disease and a radiological appearance that has
multiple causes and can be associated with a range of conditions. Disease heterogeneity …

Severe pneumonia is associated with high mortality (short and long term), as well as
pulmonary and extrapulmonary complications. Appropriate diagnosis and early initiation of …

Bronchiectasis, a progressive chronic airway disease, is characterized by microbial
colonization and infection. We present an approach to the multi-biome that integrates …

Background Infection is a key component of bronchiectasis pathophysiology.
Characterisation of the microbiome offers a higher degree of sensitivity and resolution than …

Abstract 16S rRNA gene profiling, which contains nine hypervariable regions (V1–V9), is the
gold standard for identifying taxonomic units by high-throughput sequencing. Microbiome …

Chronic respiratory diseases including chronic rhinosinusitis, otitis media, asthma, cystic
fibrosis, non-CF bronchiectasis, and chronic obstructive pulmonary disease are a major …

Bronchiectasis is increasing in prevalence worldwide, yet current treatments available are
limited to those alleviating symptoms and reducing exacerbations. The pathogenesis of the …

Bronchiectasis is a complex, heterogeneous disorder defined by both a radiological
abnormality of permanent bronchial dilatation and a clinical syndrome. There are multiple …

Introduction: Bronchiectasis is a chronic endobronchial suppurative disease characterized
by irreversibly dilated bronchi damaged by repeated polymicrobial infections and …

Objective To review the airway microbiome in chronic obstructive pulmonary disease
(COPD), bronchiectasis and bronchiectasis‐COPD overlap (BCO). Data source and study …