[HTML][HTML] The Research Progress in Transforming Growth Factor-β2

MY Wang, WJ Liu, LY Wu, G Wang, CL Zhang, J Liu - Cells, 2023 - mdpi.com
Transforming growth factor-beta 2 (TGF-β2), an important member of the TGF-β family, is a
secreted protein that is involved in many biological processes, such as cell growth …

[HTML][HTML] Anti-Inflammatory Role of the Klotho Protein and Relevance to Aging

GJ Prud'homme, Q Wang - Cells, 2024 - mdpi.com
The α-Klotho protein (hereafter Klotho) is an obligate coreceptor for fibroblast growth factor
23 (FGF23). It is produced in the kidneys, brain and other sites. Klotho insufficiency causes …

[HTML][HTML] Epithelial-mesenchymal Transition (EMT) and the Effect of Atorvastatin on it in ARPE-19 cells

Y Mysore, M Hytti, AJ Deen, S Ranta-Aho… - Cell Biochemistry and …, 2024 - Springer
Proliferative vitreoretinopathy (PVR) develops after an unsuccessful or complicated recovery
from rhegmatogenous retinal detachment (RRD) surgery. Intraocular scar formation with the …

Autophagy in dry AMD: a promising therapeutic strategy for retinal pigment epithelial cell damage

Z Zhang, F Liang, J Chang, X Shan, Z Yin… - Experimental Eye …, 2024 - Elsevier
Dry age-related macular degeneration (AMD) is a prevalent clinical condition that leads to
permanent damage to central vision and poses a significant threat to patients' visual health …

[HTML][HTML] Absence of the Klotho Function Causes Cornea Degeneration with Specific Features Resembling Fuchs Endothelial Corneal Dystrophy and Bullous …

CY Wu, DF Song, ZJ Chen, CS Hu, DPC Lin… - Biology, 2024 - mdpi.com
Simple Summary The Klotho null mutation leads to accelerated senescence in many organs.
The effects of an absence of the Klotho function on the cornea remain largely unknown. This …

Local vascular Klotho mediates diabetes-induced atherosclerosis via ERK1/2 and PI3-kinase-dependent signaling pathways

AK Ajay, LJ Zhu, L Zhao, Q Liu, Y Ding, YC Chang… - Atherosclerosis, 2024 - Elsevier
Background and aims Diabetes is one of the major causes of cardiovascular disease (CVD).
As high as 29% of patients with diabetes develop atherosclerosis. Vascular Smooth Muscle …