Exploring molecular mechanisms, therapeutic strategies, and clinical manifestations of Huntington's disease

A Shafie, AA Ashour, S Anwar, F Anjum… - Archives of Pharmacal …, 2024 - Springer
Huntington's disease (HD) is a paradigm of a genetic neurodegenerative disorder
characterized by the expansion of CAG repeats in the HTT gene. This extensive review …

Pathomechanisms of behavioral abnormalities in Huntington disease: an update

KA Jellinger - Journal of Neural Transmission, 2024 - Springer
Huntington disease (HD), a devastating autosomal-dominant neurodegenerative disease
caused by an expanded CAG trinucleotide repeat, is clinically characterized by a triad of …