ERK: a key player in the pathophysiology of cardiac hypertrophy

S Gallo, A Vitacolonna, A Bonzano, P Comoglio… - International journal of …, 2019 - mdpi.com
Cardiac hypertrophy is an adaptive and compensatory mechanism preserving cardiac
output during detrimental stimuli. Nevertheless, long-term stimuli incite chronic hypertrophy …

2009 focused update incorporated into the ACC/AHA 2005 Guidelines for the Diagnosis and Management of Heart Failure in Adults: a report of the American College …

2005 Writing Committee Members, SA Hunt… - Circulation, 2009 - Am Heart Assoc
It is important that the medical profession play a significant role in critically evaluating the
use of diagnostic procedures and therapies as they are introduced and tested in the …

ACC/AHA 2005 guideline update for the diagnosis and management of chronic heart failure in the adult: a report of the American College of Cardiology/American …

Writing Committee Members, SA Hunt, WT Abraham… - circulation, 2005 - Am Heart Assoc
Heart failure (HF) is a major and growing public health problem in the United States.
Approximately 5 million patients in this country have HF, and over 550 000 patients are …

Cardiac hypertrophy: the good, the bad, and the ugly

N Frey, EN Olson - Annual review of physiology, 2003 - annualreviews.org
▪ Abstract Cardiac hypertrophy is the heart's response to a variety of extrinsic and intrinsic
stimuli that impose increased biomechanical stress. While hypertrophy can eventually …

Biomarkers of cardiovascular disease: molecular basis and practical considerations

RS Vasan - Circulation, 2006 - Am Heart Assoc
echocardiogram) may be expected to facilitate the identification of patients with chest pain of
an ischemic etiology (angina). In a patient presenting to the emergency department with …

Myocardial remodeling in hypertension

W Nadruz - Journal of human hypertension, 2015 - nature.com
Left ventricular (LV) hypertrophy and remodeling are frequently seen in hypertensive
subjects and result from a complex interaction of several hemodynamic and non …

Prognostic significance of left ventricular mass change during treatment of hypertension

RB Devereux, K Wachtell, E Gerdts, K Boman… - Jama, 2004 - jamanetwork.com
ContextIncreased baseline left ventricular (LV) mass predicts cardiovascular (CV)
complications of hypertension, but the relation between lower LV mass and outcome during …

Prevalence of left-ventricular hypertrophy in hypertension: an updated review of echocardiographic studies

C Cuspidi, C Sala, F Negri, G Mancia… - Journal of human …, 2012 - nature.com
Left-ventricular hypertrophy (LVH) is a cardinal manifestation of hypertensive organ damage
associated with an increased cardiovascular (CV) risk. We reviewed recent literature on the …

Worldwide trends in prevalence, mortality, and disability-adjusted life years for hypertensive heart disease from 1990 to 2017

H Dai, NL Bragazzi, A Younis, W Zhong, X Liu, J Wu… - …, 2021 - Am Heart Assoc
Hypertensive heart disease (HHD) is a major cause of global morbidity and mortality.
Understanding its current burden among various countries and populations is crucial for …

Regulatory T cells ameliorate angiotensin II–induced cardiac damage

H Kvakan, M Kleinewietfeld, F Qadri, JK Park… - Circulation, 2009 - Am Heart Assoc
Background—Hypertensive target organ damage, especially cardiac hypertrophy with heart
failure and arrhythmia, is a major source of morbidity and mortality. Angiotensin II, a major …