The Crc protein inhibits the production of polyhydroxyalkanoates in Pseudomonas putida under balanced carbon/nitrogen growth conditions
P seudomonas putida synthesizes polyhydroxyalkanoates (PHAs) as storage compounds.
PHA synthesis is more active when the carbon source is in excess and the nitrogen source …
PHA synthesis is more active when the carbon source is in excess and the nitrogen source …
Quantitative proteomics unravels that the post-transcriptional regulator Crc modulates the generation of vesicles and secreted virulence determinants of Pseudomonas …
Recent research indicates that the post-transcriptional regulator Crc modulates susceptibility
to antibiotics and virulence in Pseudomonas aeruginosa. Several P. aeruginosa virulence …
to antibiotics and virulence in Pseudomonas aeruginosa. Several P. aeruginosa virulence …
Machine learning analysis of RB-TnSeq fitness data predicts functional gene modules in Pseudomonas putida KT2440
There is growing interest in engineering Pseudomonas putida KT2440 as a microbial
chassis for the conversion of renewable and waste-based feedstocks, and metabolic …
chassis for the conversion of renewable and waste-based feedstocks, and metabolic …
The β-ketoadipate pathway of Acinetobacter baylyi undergoes carbon catabolite repression, cross-regulation and vertical regulation, and is affected by Crc
FS Bleichrodt, R Fischer, UC Gerischer - Microbiology, 2010 - microbiologyresearch.org
The degradation of many structurally diverse aromatic compounds in Acinetobacter baylyi is
accomplished by the β-ketoadipate pathway. In addition to specific induction of expression …
accomplished by the β-ketoadipate pathway. In addition to specific induction of expression …
Small RNAs regulate primary and secondary metabolism in Gram‐negative bacteria
M Bobrovskyy, CK Vanderpool… - Metabolism and …, 2015 - Wiley Online Library
A diverse palette of novel small regulatory RNAs (sRNAs) has been identified in bacteria in
recent years, and many play important roles in regulating gene expression and adaptation to …
recent years, and many play important roles in regulating gene expression and adaptation to …
Effect of Crc and Hfq proteins on the transcription, processing, and stability of the Pseudomonas putida CrcZ sRNA
S Hernández-Arranz, D Sánchez-Hevia, F Rojo… - Rna, 2016 - rnajournal.cshlp.org
In Pseudomonas putida, the Hfq and Crc proteins regulate the expression of many genes in
response to nutritional and environmental cues, by binding to mRNAs that bear specific …
response to nutritional and environmental cues, by binding to mRNAs that bear specific …
Optimal bioprocess design through a gene regulatory network–Growth kinetic hybrid model: Towards replacing Monod kinetics
Currently, design and optimisation of biotechnological bioprocesses is performed either
through exhaustive experimentation and/or with the use of empirical, unstructured growth …
through exhaustive experimentation and/or with the use of empirical, unstructured growth …
The antibiotic resistome: challenge and opportunity for therapeutic intervention
JL Martínez - Future medicinal chemistry, 2012 - Future Science
Despite the relevance of infectious disease as main causes of human morbidity and
mortality, the development of new antibacterials is not among the highest priorities for …
mortality, the development of new antibacterials is not among the highest priorities for …
[HTML][HTML] Computational prediction of the Crc regulon identifies genus-wide and species-specific targets of catabolite repression control in Pseudomonas bacteria
Background Catabolite repression control (CRC) is an important global control system in
Pseudomonas that fine tunes metabolism in order optimise growth and metabolism in a …
Pseudomonas that fine tunes metabolism in order optimise growth and metabolism in a …
Role of Acinetobacter baylyi Crc in Catabolite Repression of Enzymes for Aromatic Compound Catabolism
T Zimmermann, T Sorg, SY Siehler… - Journal of …, 2009 - Am Soc Microbiol
Here, we describe for the first time the Crc (c atabolite r epression c ontrol) protein from the
soil bacterium Acinetobacter baylyi. Expression of A. baylyi crc varied according to the …
soil bacterium Acinetobacter baylyi. Expression of A. baylyi crc varied according to the …