Due to emergence of new variants of pathogenic micro-organisms the treatment and
immunization of infectious diseases have become a great challenge in the past few years. In …

Cancer immunotherapy has become a new generation of anti-tumor treatment, but its
indications still focus on several types of tumors that are sensitive to the immune system …

Oligodendrocyte precursor cells (OPCs) are abundant in the adult central nervous system,
and have the capacity to regenerate oligodendrocytes and myelin. However, in inflammatory …

The immune system plays a critical role in our health. No other component of human
physiology plays a decisive role in as diverse an array of maladies, from deadly diseases …

Personalized cancer vaccines (PCVs) are reinvigorating vaccine strategies in cancer
immunotherapy. In contrast to adoptive T-cell therapy and checkpoint blockade, the PCV …

T cell recognition of antigen-presenting cells depends on their expression of a spectrum of
peptides bound to major histocompatibility complex class I (MHC-I) and class II (MHC-II) …

Dendritic cells (DCs) form a remarkable cellular network that shapes adaptive immune
responses according to peripheral cues. After four decades of research, we now know that …

The lower immunogenicity of synthetic subunit antigens, compared to live attenuated
vaccines, is being addressed with improved vaccine carriers. Recent reports indicate that …

Neoantigens induced by random mutations and specific to an individual's cancer are the
most important tumor antigens recognized by T cells. Among immunologically “cold” tumors …

Atlantic cod (Gadus morhua) is a large, cold-adapted teleost that sustains long-standing
commercial fisheries and incipient aquaculture,. Here we present the genome sequence of …