Drug repositioning: doxazosin attenuates the virulence factors and biofilm formation in Gram-negative bacteria

MA Elfaky, SS Elbaramawi, AG Eissa… - Applied Microbiology …, 2023 - Springer
The resistance development is an increasing global health risk that needs innovative
solutions. Repurposing drugs to serve as anti-virulence agents is suggested as an …

Quorum sensing inhibitors applications: a new prospect for mitigation of microbiologically influenced corrosion

A Lamin, AH Kaksonen, IS Cole, XB Chen - Bioelectrochemistry, 2022 - Elsevier
Quorum sensing (QS) is a process of bacterial communication that involves the use of
biochemical signals and adjusts the expression of specific genes as a response to the …

Friends or foes—microbial interactions in nature

N Weiland-Bräuer - Biology, 2021 - mdpi.com
Simple Summary Microorganisms like bacteria, archaea, fungi, microalgae, and viruses
mostly form complex interactive networks within the ecosystem rather than existing as single …

Anti-quorum sensing and antimicrobial effect of Mediterranean plant essential oils against phytopathogenic bacteria

I Camele, HS Elshafie, L Caputo, V De Feo - Frontiers in Microbiology, 2019 - frontiersin.org
Essential oils (EOs) are one of the most interesting natural products extracted from different
aromatic plants. For centuries, EOs have been considered an essential part of the traditional …

Multimodal role of amino acids in microbial control and drug development

M Idrees, AR Mohammad, N Karodia, A Rahman - Antibiotics, 2020 - mdpi.com
Amino acids are ubiquitous vital biomolecules found in all kinds of living organisms
including those in the microbial world. They are utilised as nutrients and control many …

Approaches to targeting bacterial biofilms in cystic fibrosis airways

I Martin, V Waters, H Grasemann - International Journal of Molecular …, 2021 - mdpi.com
The treatment of lung infection in the context of cystic fibrosis (CF) is limited by a biofilm
mode of growth of pathogenic organisms. When compared to planktonically grown bacteria …

Cancer cell population growth kinetics at low densities deviate from the exponential growth model and suggest an Allee effect

KE Johnson, G Howard, W Mo, MK Strasser… - PLoS …, 2019 - journals.plos.org
Most models of cancer cell population expansion assume exponential growth kinetics at low
cell densities, with deviations to account for observed slowing of growth rate only at higher …

Recent advances in the control of clinically important biofilms

K Krukiewicz, A Kazek-Kęsik… - International journal of …, 2022 - mdpi.com
Biofilms are complex structures formed by bacteria, fungi, or even viruses on biotic and
abiotic surfaces, and they can be found in almost any part of the human body. The …

[HTML][HTML] What's old is new again: Insights into diabetic foot microbiome

AAH Rajab, WAH Hegazy - World Journal of Diabetes, 2023 - ncbi.nlm.nih.gov
Diabetes is a chronic disease that is considered one of the most stubborn global health
problems that continues to defy the efforts of scientists and physicians. The prevalence of …

Repurposing Anti-diabetic Drugs to Cripple Quorum Sensing in Pseudomonas aeruginosa

WAH Hegazy, MT Khayat, TS Ibrahim, MS Nassar… - Microorganisms, 2020 - mdpi.com
Pseudomonas aeruginosa is a significant human pathogen, it possesses almost all of the
known antimicrobial resistance mechanisms. Quorum sensing (QS) is an intercellular …