1, 2, 3-triazole derivatives with anti-breast cancer potential

X Wu, J Wang, S Xia, S Cheng… - Current Topics in …, 2022 - ingentaconnect.com
Breast cancer is one of the most prevalent malignant diseases, and one of the main causes
of mortality among women across the world. Despite advances in chemotherapy, drug …

Recent developments of quinoline derivatives and their potential biological activities

M Dib, H Ouchetto, K Ouchetto, A Hafid… - Current Organic …, 2021 - ingentaconnect.com
Heterocyclic compounds containing the quinoline ring play a significant role in organic
synthesis and therapeutic chemistry. Polyfunctionalized quinolines have attracted the …

Photo-thermo-mechanochemical approach to synthesize quinolines via addition/cyclization of sulfoxonium ylides with 2-vinylanilines catalyzed by iron (II) …

L Liu, J Lin, M Pang, H Jin, X Yu, S Wang - Organic Letters, 2022 - ACS Publications
A novel photo-thermo-mechanochemical approach to assembling quinolines catalyzed by
iron (II) phthalocyanine has been realized for the first time. This transformation features a …

Photocatalytic aerobic dehydrogenation of N-heterocycles with Ir (III) photosensitizers bearing the 2 (2′-Pyridyl) benzimidazole scaffold

I Echevarría, M Vaquero, BR Manzano… - Inorganic …, 2022 - ACS Publications
Photoredox catalysis constitutes a very powerful tool in organic synthesis, due to its
versatility, efficiency, and the mild conditions required by photoinduced transformations. In …

Synthesis of Quinoline-2-thiones by Selective Deoxygenative CH/CS Functionalization of Quinoline N-Oxides with Thiourea

DI Bugaenko, OA Tikhanova… - The Journal of Organic …, 2023 - ACS Publications
Quinoline-2-thiones valuable for synthetic and medicinal chemistry applications were
obtained with excellent regioselectivity employing a deoxygenative C–H functionalization of …

Mixed Ni (II) and Co (II) complexes of nalidixic acid drug: Synthesis, characterization, DNA/BSA binding profile and in vitro cytotoxic evaluation against MDA-MB-231 …

M Bashir, I Yousuf, CP Prasad - Spectrochimica Acta Part A: Molecular and …, 2022 - Elsevier
In this work, herein we report the synthesis, structural characterization and in vitro cytotoxic
evaluation of two mixed Co (II)/Ni (II)-nalidixic acid-bipyridyl complexes (1 and 2). The …

Biology of quinoline and quinazoline alkaloids

XF Shang, SL Morris-Natschke, YQ Liu, XH Li… - The Alkaloids: Chemistry …, 2022 - Elsevier
Quinoline and quinazoline alkaloids, two important classes of N-based heterocyclic
compounds, have attracted scientific and popular interest worldwide since the 19th century …

Iodine-Promoted Metal-Free Cyclization and O/S Exchange of Acrylamides with Thiuram: One-Step Synthesis of Quinolino-2-thiones

J Jiao, F Xiao, C Wang, Z Zhang - The Journal of Organic …, 2022 - ACS Publications
A one-step cyclization and O/S exchange reaction of readily available acrylamides in the
presence of iodine and thiuram has been developed. The reaction provides an efficient …

An insight into sustainable and green chemistry approaches for the synthesis of quinoline derivatives as anticancer agents

B Kumaraswamy, K Hemalatha, R Pal… - European Journal of …, 2024 - Elsevier
Quinolones, a key class of heterocyclics, are gaining popularity among organic and
medicinal chemists due to their promising properties. Quinoline, with its broad spectrum of …

Synthesis, anti-proliferative activity, DFT and docking studies of some novel chloroquinoline-based heterocycles

MF Ismail, A Aboelnaga, MM Naguib… - Polycyclic Aromatic …, 2023 - Taylor & Francis
Cancer is one of the leading causes of death. Quinoline is well known as one of the most
potent pharmaceutically active scaffolds with remarkable pharmacological properties. So, in …