Current concepts of biomaterial scaffolds and regenerative therapy for spinal cord injury

H Suzuki, Y Imajo, M Funaba, H Ikeda… - International Journal of …, 2023 - mdpi.com
Spinal cord injury (SCI) is a catastrophic condition associated with significant neurological
deficit and social and financial burdens. It is currently being managed symptomatically, with …

Hydrogel and nanomedicine‐based multimodal therapeutic strategies for spinal cord injury

P Yin, W Liang, B Han, Y Yang, D Sun, X Qu… - Small …, 2024 - Wiley Online Library
Spinal cord injury (SCI) is a severe neurodegenerative disease caused by mechanical and
biological factors, manifesting as a loss of motor and sensory functions. Inhibition of injury …

Growth Factor Immobilization to Synthetic Hydrogels: Bioactive bFGF‐Functionalized Polyisocyanide Hydrogels

MJJ van Velthoven, AN Gudde… - Advanced …, 2023 - Wiley Online Library
With its involvement in cell proliferation, migration and differentiation basic fibroblast growth
factor (bFGF) has great potential for tissue engineering purposes. So far, however, clinical …

Application of injectable hydrogels as delivery Systems in Spinal Cord Injury

R Ji, Z Hao, H Wang, X Li, L Duan, F Guan, S Ma - Gels, 2023 - mdpi.com
Spinal cord injury (SCI) is a severe neurological injury caused by traffic accidents, trauma, or
falls, which leads to significant loss of sensory, motor, and autonomous functions and …

Interactions of Cells and Biomaterials for Nerve Tissue Engineering: Polymers and Fabrication

ME Harley-Troxell, R Steiner, RC Advincula… - Polymers, 2023 - mdpi.com
Neural injuries affect millions globally, significantly impacting their quality of life. The inability
of these injuries to heal, limited ability to regenerate, and the lack of available treatments …

[HTML][HTML] Spinal cord conduits for spinal cord injury regeneration

Y Ma, Q Chen, W Li, H Su, S Li, Y Zhu, J Zhou… - Engineered …, 2023 - Elsevier
Spinal cord injury (SCI), which causes irreversible damage in both sensory and motor
function, is considered an insurmountable challenge in the field of medicine. The previous …

Polysaccharides as a promising platform for the treatment of spinal cord injury: A review

Y Yang, R Fan, H Li, H Chen, H Gong, G Guo - Carbohydrate Polymers, 2023 - Elsevier
Spinal cord injury is incurable and often results in irreversible damage to motor function and
autonomic sensory abilities. To enhance the effectiveness of therapeutic substances such as …

Hydrogel Encapsulation Techniques and Its Clinical Applications in Drug Delivery and Regenerative Medicine: A Systematic Review

B Farasati Far, M Safaei, R Nahavandi, A Gholami… - ACS …, 2024 - ACS Publications
Hydrogel encapsulation is a promising carrier for cell and drug delivery due to its ability to
protect the encapsulated entities from harsh physiological conditions and enhance their …

Efficacy and safety of stem cell therapy in cerebral palsy: A systematic review and meta-analysis

J Qu, L Zhou, H Zhang, D Han, Y Luo… - … in Bioengineering and …, 2022 - frontiersin.org
Aim: Although the efficacy and safety of stem cell therapy for cerebral palsy has been
demonstrated in previous studies, the number of studies is limited and the treatment …

Magnetic Nanoparticles and Methylprednisolone Based Physico‐Chemical Bifunctional Neural Stem Cells Delivery System for Spinal Cord Injury Repair

W Zhang, M Liu, J Ren, S Han, X Zhou… - Advanced …, 2024 - Wiley Online Library
Neural stem cells (NSCs) transplantation is an attractive and promising treatment strategy for
spinal cord injury (SCI). Various pathological processes including the severe inflammatory …