The acute respiratory distress syndrome (ARDS) is a life-threatening lung condition resulting
from direct and indirect insults to the lung. It is characterized by disruption of the endothelial …

Rationale: Most models of acute lung injury in mice have yet to be fully characterized.
Objectives: To directly compare and contrast endotoxin and oleic acid models of acute lung …

For drug-induced interstitial lung disease (DIILD) translational imaging biomarkers are
needed to improve detection and management of lung injury and drug-toxicity. Literature …

The alveolar epithelium is comprised of alveolar type (AT) I and ATII cells, which form a tight
barrier. During the Acute Respiratory Distress Syndrome (ARDS), the epithelium is …

Introduction Acute lung injury (ALI) may arise both after sepsis and non-septic inflammatory
conditions and is often associated with the release of fatty acids, including oleic acid (OA) …

Chronic obstructive pulmonary disease (COPD) is a lung disease characterized by airflow
obstruction from small airway remodeling and alveolar airspace destruction. As a disease …

Background The underlying pathogenesis of fat embolism-induced acute lung injury (ALI)
has not been elucidated. In the present study, the pathogenesis of fat embolism-induced ALI …

The current understanding of the pathophysiology of sepsis is that inflammation,
coagulation, and apoptosis are linked throughout the disease process [1]. Recombinant …

The acute respiratory distress syndrome (ARDS) is a common clinical manifestation of acute
lung injury (ALI) with a high mortality rate. Although improvements in supportive care and …

1 The mercurial nature of neutrophils: still an enigma in ARDS? 1 2 3 Andrew E Williams
and Rachel C Chambers 4 Centre for Infla Page 1 1 The mercurial nature of neutrophils: still …