The potential for commensal microorganisms indigenous to a host (the 'microbiome'or
'microbiota') to alter infection outcome by influencing host-pathogen interplay is largely …

Salmonella enterica subspecies can establish persistent, systemic infections in mammals,
including human typhoid fever. Persistent S. enterica disease is characterized by an initial …

Nramp1 confers resistance of macrophages to Salmonella Typhimurium via NF-κB-
dependent induction of the siderophore capturing peptide lipocalin-2. The expression of the …

Salmonella spp. are major cause of human morbidity and mortality worldwide. Upon entry
into the human host, Salmonella spp. must overcome the resistance to colonization …

Iron is an essential cofactor for several enzymes and metabolic pathways, in both microbes
and in their eukaryotic hosts. To avoid toxicity, iron acquisition is tightly regulated. This …

The natural resistance‐associated macrophage protein 1, Slc11a1, is a phagolysosomal
transporter for protons and divalent ions including iron that confers host protection against …

The fate of Leishmania infection can be strongly influenced by the host genetic background.
In this work, we describe gene expression modulation of the immune system based on dual …

Antagonistic coevolution (ie, reciprocal adaptation and counter-adaptation) between hosts
and pathogens has long been considered an important driver of genetic variation. However …

There are many lines of evidence illustrating that iron plays a pivotal role in modulating the
battle for survival between mammalian hosts and their pathogens. Each displays …

Genetic susceptibility to visceral leishmaniasis (VL) is indicated by differences in incidence
and clinical phenotypes between ethnic groups in Sudan. In mice, innate susceptibility to …