Leishmania species are causative agents of human leishmaniasis, affecting 12 million
people annually. Drugs available for leishmaniasis are toxic, and no vaccine is available …

Tuberculosis (TB) is a global epidemic caused by the infection of human macrophages with
the world's most deadly single bacterial pathogen, Mycobacterium tuberculosis (M. tb). M. tb …

Individuals in natural populations are frequently exposed to a wide range of pathogens.
Given the diverse profile of gene products involved in responses to different types of …

The protozoan parasite Leishmania experiences extreme environmental changes as it
alternates between insect and mammalian hosts. In some species, differentiation of insect …

Analysis of global gene expression in immune cells has provided unique insights into
immune system function and response to infection. Recently, we applied microarray and …

Solute carrier 11a1 (Slc11a1; formerly Nramp1; where Nramp stands for natural-resistance-
associated macrophage protein) is a proton/bivalent cation antiporter that localizes to late …

Parasites of genus Leishmania are the causative agents of complex neglected diseases
called leishmaniasis and continue to be a significant health concern globally. Iron is a vital …

Host genetics in dengue hemorrhagic fever (DHF) pathophysiology has not been
extensively investigated. Most studies have focused on HLA in different populations; …

Solute carrier family 11 member a1 (Slc11a1; formerly Nramp1) encodes a late
endosomal/lysosomal protein/divalent cation transporter that regulates iron homeostasis in …

Background Iron deficiency can impair immune function, increasing tuberculosis (TB)
susceptibility and severity. The research aimed to investigate iron deficiency anemia in TB …