Alteration in brain metabolism predates clinical onset of Alzheimer's Disease (AD). Realizing
its potential as an early diagnostic marker, however, requires understanding how early AD …

For non-bovine milks, information regarding bioactive lipids is fragmented, unreliable or
unavailable. The purpose of the current study was to analyse bioactive lipids in the milk of …

Brain-Derived Neurotropic Factor (BDNF) expression is decreased in conditions associated
with cognitive decline as well as metabolic diseases. One potential strategy to improve …

Astrocytes regulate local cerebral blood flow, maintain ion and neurotransmitter
homeostasis, provide metabolic support, regulate synaptic activity, and respond to brain …

This review discusses the effects and mechanisms of a ketogenic diet on neurodegenerative
diseases on the basis of available evidence. A ketogenic diet refers to a high-fat, medium …

Modern healthcare systems are founded on a disease-centric paradigm, which has
conferred many notable successes against infectious disorders in the past. However, today's …

Carriers of an epsilon 4 allele (E4) of apolipoprotein E (APOE) develop Alzheimer's disease
(AD) earlier than carriers of other APOE alleles. The metabolism of plasma …

Background Studies have consistently shown that patients with epilepsy could benefit from
ketogenic diets (KDs). Recent evidence suggests that KD could be used in the treatment of …

The most commonly used vaccine worldwide, bacillus Calmette–Guerin (BCG), appears to
have the ability to restore blood sugar control in humans with early‐onset but long‐duration …

Mitochondrial dysfunction is pivotal in the development of neurodegenerative dementias,
causing cellular death alongside disease-specific pathogenic cascades. Holding …