[HTML][HTML] Characterization of glomerular diseases using proteomic analysis of laser capture microdissected glomeruli
AA Satoskar, JP Shapiro, CN Bott, H Song… - Modern Pathology, 2012 - Elsevier
The application of molecular techniques to characterize clinical kidney biopsies has the
potential to provide insights into glomerular diseases that cannot be revealed by traditional …
potential to provide insights into glomerular diseases that cannot be revealed by traditional …
Profiling and annotation of human kidney glomerulus proteome
Z Cui, Y Yoshida, B Xu, Y Zhang, M Nameta… - Proteome science, 2013 - Springer
Background The comprehensive analysis of human kidney glomerulus we previously
performed using highly purified glomeruli, provided a dataset of 6,686 unique proteins …
performed using highly purified glomeruli, provided a dataset of 6,686 unique proteins …
[PDF][PDF] Proteomic patterns in glomerular research, a laser capture microdissection and liquid chromatography-tandem mass spectrometry approach
AA Bărar, IE Pralea, I Berindan-Neagoe… - Revista Romana de …, 2023 - sciendo.com
Introduction: Molecular techniques have the potential to shed light on glomerular diseases
that conventional renal pathology may be unable to reveal. The aim of this study was to …
that conventional renal pathology may be unable to reveal. The aim of this study was to …
Imaging mass spectrometry reveals direct albumin fragmentation within the diabetic kidney
Albumin degradation in the renal tubules is impaired in diabetic nephropathy such that
levels of the resulting albumin fragments increase with the degree of renal injury. However …
levels of the resulting albumin fragments increase with the degree of renal injury. However …
Proteomic approach to human kidney glomerulus prepared by laser microdissection from frozen biopsy specimens: Exploration of proteome after removal of blood …
Y Yoshida, M Nameta, M Kuwano… - PROTEOMICS …, 2012 - Wiley Online Library
Purpose Abundance of blood‐derived proteins in glomeruli prepared by laser
microdissection from human kidney biopsy specimens has hampered in‐depth proteomic …
microdissection from human kidney biopsy specimens has hampered in‐depth proteomic …
Opening a treasure chest: glomerular proteome analyses of formalin-fixed paraffin-embedded kidney tissue in the investigation of diabetic nephropathy
A Blutke - Nephrology Dialysis Transplantation, 2012 - academic.oup.com
Worldwide, diabetic nephropathy (DN) persists as a major complication of diabetes mellitus
(DM), affecting approximately one-third of DM patients [1]. DN is characterized by …
(DM), affecting approximately one-third of DM patients [1]. DN is characterized by …
Micro-sieving: isolation of whole glomeruli from a single renal needle biopsy sample
K Koitabashi, K Okamoto, M Arirto, T Sato… - Nephron Clinical …, 2011 - karger.com
Renal biopsy samples are important not only for the diagnosis of glomerulonephritis, but
also for the investigation of its pathogenesis. However, it remains difficult to biochemically …
also for the investigation of its pathogenesis. However, it remains difficult to biochemically …
Imaging mass spectrometry for the elucidation of lipid and protein changes in diabetic nephropathy and assessment of drug efficacy
KJ Grove - 2014 - ir.vanderbilt.edu
Diabetic nephropathy (DN) leads to progressive decline in renal function and is the leading
cause of end-stage renal disease. Much still remains unknown about the pathogenesis of …
cause of end-stage renal disease. Much still remains unknown about the pathogenesis of …