Osteoarthritis (OA) is one of the most debilitating diseases and is associated with a high
personal and socioeconomic burden. So far, there is no therapy available that effectively …

Ageing-associated changes that affect articular tissues promote the development of
osteoarthritis (OA). Although ageing and OA are closely linked, they are independent …

In diarthrodial joints, the articular cartilage, calcified cartilage, and subchondral cortical and
trabecular bone form a biocomposite—referred to as the osteochondral unit—that is …

Osteoarthritis (OA), is a major cause of severe joint pain, physical disability and quality of life
impairment in the aging population across the developed and developing world. Increased …

Introduction Osteoarthritis (OA) is one of the most common forms of arthritis. There is
accumulating evidence to suggest that OA is an inflammatory disease of the entire synovial …

Osteoarthritis (OA) is the most prevalent chronic rheumatic diseases worldwide, with a
strong impact on individual and population health. OA is a clinically heterogeneous disease …

Synovial joints are complex structures that enable normal locomotion. Following injury, they
undergo a series of changes, including a prevalent inflammatory response. This increases …

Objectives Type 2 diabetes mellitus (T2DM) and osteoarthritis (OA) are common diseases
that frequently co-exist, along with overweight/obesity. While the mechanical impact of …

Pain due to osteoarthritis (OA) is one of the most frequent causes of chronic pain. However,
the mechanisms of OA pain are poorly understood. This review addresses the mechanisms …

Metabolic syndrome-associated osteoarthritis : Current Opinion in Rheumatology Metabolic
syndrome-associated osteoarthritis : Current Opinion in Rheumatology Log in or Register …